Supplementary Material for: Genetical predicted causal relationship between gut microbiota and different types of kidney diseases by figshare admin karger (2628495)

“…No significant pleiotropy or heterogeneity was identified. …”

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg by Ling Hu (374570)

“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”

Supplementary Material for: DOT1L regulates cellular senescence during the progression from acute kidney injury to chronic kidney disease via the micro-222-5p/WNT9B signaling pathw... by figshare admin karger (2628495)

“…In the doxorubicin -induced HK-2 cell model, DOT1L inhibition markedly decreased cellular senescence and lowered mRNA and protein levels of senescence markers, while alleviating cell cycle arrest. …”

Table 3_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Table 4_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Data Sheet 2_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.pdf by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Data Sheet 1_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.pdf by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

<b>Data for opposing effects</b><b> of maize straw and its biochar on soil N</b>_{<strong>2</strong>}<b>O emissions</b><b> </b><b>by mediating microbial nitrification and d... by MOULIANG XIAO (21266015)

“…<p dir="ltr">Application of straw and biochar has been shown to significantly affect greenhouse gas emissions from soil. …”

All source data of the paper “The mimicking and synergistic effects of magnetic fields on caloric restriction” by Xin Zhang (17292393)

“…Nonetheless, maintaining strict long-term compliance to CR and overcome its the metabolic adaptation have proven to be significant challenges. In this study, we discovered that combining CR with magnetic fields (MFs), a straightforward physical intervention, can increase the ATP production and mitochondrial respiration in liver cells. …”

Table 3_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Table 1_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Table 2_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Table 5_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Table 6_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.docx by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of... by Long Chen (315739)

“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1 by Salvador García-Carmona (20580797)

“…The aim of this study was to assess the changes that genetic material can exhibit and their impact on the production of proteins involved in the disease.</p> <p>We found a significant effect on genes that play roles in inflammation and detoxification processes in the body. …”

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data Sheet 1_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.pdf by Renshengjie Zhao (22459771)

“…Using siRNA gene knockdown technology, we suppressed NRIR and RSAD2 expression in M1 macrophages derived from THP-1 cells. …”