Key safety measures including adverse events. by Anuja Dokras (8679261)

“…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…”

Supplementary file 1_Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, con... by Chin-Yi Yang (8104340)

“…The proportion of Staphylococcus aureus species in AD lesions significantly decreased after both treatments, and was not different from that of non-lesion skin.…”

The basic flowchart of analysis in this study. by Jing Wang (6206297)

“…Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.</p><p>Conclusion</p><p>This study examined changes in intercellular communication between immune cells in the peripheral blood and identified five novel feature genes associated with cuproptosis in AD patients. …”

The enriched GO terms of the 19 DECAGs. by Jing Wang (6206297)

“…Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.</p><p>Conclusion</p><p>This study examined changes in intercellular communication between immune cells in the peripheral blood and identified five novel feature genes associated with cuproptosis in AD patients. …”

Primers of the tested genes. by Jing Wang (6206297)

“…Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.</p><p>Conclusion</p><p>This study examined changes in intercellular communication between immune cells in the peripheral blood and identified five novel feature genes associated with cuproptosis in AD patients. …”

Summary of patient demographic characteristics. by Jing Wang (6206297)

“…Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.</p><p>Conclusion</p><p>This study examined changes in intercellular communication between immune cells in the peripheral blood and identified five novel feature genes associated with cuproptosis in AD patients. …”

Evaluation of the bactericidal effect of far UV-C irradiation for the peritonitis rat model in the hyper-acute phase. by Kosuke Sugiyama (10042051)

“…The bacterial concentration and serum IL-1β and IL-6 levels significantly decreased in the irradiated peritonitis group (**<i>p</i> < 0.01, Student’s <i>t</i>-test). …”

Qualitative changes in the implant subgroup. by Adela Klezlova (22608008)

“…There was one scleral extrusion of the device, which was, in our opinion, caused by insufficient conjunctival fixation. A statistically significant IOP reduction was achieved at the end of the follow-up in the study group with implanted GDIs. …”

Results of the colorimetric MTT test. by Adela Klezlova (22608008)

“…There was one scleral extrusion of the device, which was, in our opinion, caused by insufficient conjunctival fixation. A statistically significant IOP reduction was achieved at the end of the follow-up in the study group with implanted GDIs. …”

IOP fluctuation. by Adela Klezlova (22608008)

“…There was one scleral extrusion of the device, which was, in our opinion, caused by insufficient conjunctival fixation. A statistically significant IOP reduction was achieved at the end of the follow-up in the study group with implanted GDIs. …”

IOP fluctuation. by Adela Klezlova (22608008)

“…There was one scleral extrusion of the device, which was, in our opinion, caused by insufficient conjunctival fixation. A statistically significant IOP reduction was achieved at the end of the follow-up in the study group with implanted GDIs. …”

Data Sheet 1_Analysis of serum amino acids and tryptophan metabolites to predict hepatic encephalopathy in portal hypertension patients receiving a transjugular intrahepatic portal... by Li Bao (323211)

“…Introduction<p>The incidence of hepatic encephalopathy (HE) after transjugular intrahepatic portal shunt (TIPS) is over 30%, how to decrease the occurrence rate of HE is one of the most challenging issues after TIPS surgery. …”

Imformation. by Shicheng Luo (14349225)

“…Flow cytometry revealed a significant decrease in the apoptosis of HK-2 cells. …”

DataSheet1_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”

DataSheet2_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”

Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled... by Jilei Hu (10156880)

“…Intestine microbial composition was analyzed by metagenomic sequencing.</p>Results<p>After a 1-week intervention on the plain, curcumin significantly increased red blood cells (RBC), hematocrit (HCT), and hemoglobin in treatment group as compared to placebo group (p < 0.05). …”

DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi... by Yanjun Liang (4394089)

“…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …”

Scale scores of all participants. by Sylwia Sumińska (21169999)

“…In contrast, in the MBSR group without smartwatches, there was a significant decrease across multiple stress-related components, including: anxiety, cognitive impairment, addictions, sleep disorders symptoms, behaviors indicating lack of entertainment, and poor functioning.…”

Table 1_Decadal trends and regional disparities in tuberculosis burden: a comprehensive analysis of global, African, and Southeast Asian data from the GBD 1990–2021.docx by Shiwei Xie (3617159)

“…</p>Conclusion<p>TB remains a significant public health issue, especially in Africa and Southeast Asia. …”