Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

DataSheet2_Association of metabolic score for insulin resistance with progression or regression of prediabetes: evidence from a multicenter Chinese medical examination cohort study... by Guotai Sheng (9707713)

“…Additionally, a nonlinear relationship between MetS-IR and prediabetes regression was observed, with 37.22 identified as the inflection point; prediabetes regression rates were significantly higher before this point and markedly decreased after it.…”

DataSheet1_Association of metabolic score for insulin resistance with progression or regression of prediabetes: evidence from a multicenter Chinese medical examination cohort study... by Guotai Sheng (9707713)

“…Additionally, a nonlinear relationship between MetS-IR and prediabetes regression was observed, with 37.22 identified as the inflection point; prediabetes regression rates were significantly higher before this point and markedly decreased after it.…”

Additional file 16 of Recombination and transposition drive genomic structural variation potentially impacting life history traits in a host-generalist fungal plant pathogen by Mark C. Derbyshire (5841785)

“…Red cells are for test statistics that indicate a decrease in SV impact on phenotype.…”

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf by Zhen Wang (72451)

“…The prevalence of abnormal blood glucose markers—FBG, 2h OGTT, and HbA1C—significantly decreased within each intervention group after short-term intervention and 6 months of follow-up. …”

Video 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.mp4 by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

Table 3_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…Both acute and chronic exercise induce a transient shift in organic homeostasis, modulating the immune system and impacting the balance between Th1 and Th2 cells. …”

DataSheet1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.PDF by Cong Zhang (582922)

“…However, Crohn’s disease (CD) (OR = 1.023, 95% CI = 0.993-1.055, p = 0.134) did not show a causal association with the risk of AP. Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

DataSheet1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.PDF by Cong Zhang (582922)

“…However, Crohn’s disease (CD) (OR = 1.023, 95% CI = 0.993-1.055, p = 0.134) did not show a causal association with the risk of AP. Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Table 4_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…Both acute and chronic exercise induce a transient shift in organic homeostasis, modulating the immune system and impacting the balance between Th1 and Th2 cells. …”

Data Sheet 1_Clinical predictors and concomitant antiseizure medications effects on seizure control in relation to plasma cenobamate concentration: a multicenter retrospective stud... by Francesca Felicia Operto (12509263)

“…Among responders, 53.8% (14/26) achieved response on ≤100 mg/day, with CNBp of 0.5–17.6 μg/mL (median ∼5–6 μg/mL). There was no significant relationship between age and gender, although there was a statistically significant correlation between CNBp and BMI (p = 0.038; R2 = 0.157). …”

Supplementary Figure 4 from A Pilot Study of the CD38 Antagonist Daratumumab in Patients with Metastatic Renal Cell Carcinoma or Muscle-Invasive Bladder Cancer by Matthew T. Campbell (15096440)

“…<p>Flow cytometry of immune cells from serially collected blood samples with evidence of significant decrease in circulating NK cells in: A) Metastatic renal cell carcinoma cohort. …”

Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx by Elia Asanterabi Swai (15337336)

“…Introduction<p>Caring for physically disabled children, particularly in contexts where resources are often insufficient or absent, exposes primary carers to significant psychological strain. The lack of structured mechanisms to address this psychological burden poses a considerable threat to the wellbeing of both carers and the children with disabilities under their care. …”

Table 1_The health burden of disease attributable to low calcium intake: a comprehensive analysis of trends and socioeconomic impacts from 1990 to 2021.docx by Yanping Wang (275956)

“…Prostate cancer and DLC showed a negative directional trend but lacked statistical significance. …”

Table 1_Impact of dual residual risk of cholesterol and inflammation on adult male sex hormones: a cross-sectional study from NHANES.docx by Yang Zhou (65942)

“…In the presence of both risk factors (BR), TT decreased most significantly (β = -79.37, 95% CI [-112.74, -46.00], p < 0.0001), as did FT in the same subgroup (β = -1.00, 95% CI [-1.61, -0.40], p = 0.0012). …”

Supplementary Material for: Long-term outcomes and clinical factors associated with conventional therapy failure in intestinal Behçet’s disease: A retrospective cohort study in Jap... by figshare admin karger (2628495)

“…Concomitant glucocorticoid use significantly decreased from 12.7±11.7 mg/day at baseline to 2.4±2.5 mg/day at 1 year (p<0.001). …”

Image 1_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.jpeg by Yutong Wu (3130584)

“…As DR severity increased, the levels of three DKD indicators presented a significant upward trend compared to those in the control group, except for Hcy in the PDR subgroup. …”

Supplementary file 1_Association of prenatal trajectories of depressive and anxiety symptoms with neurodevelopment of children aged 0-24 months: A prospective study.docx by Ruoqing Chen (9952075)

“…Background<p>Prenatal depression and anxiety can significantly impact a child’s neurodevelopment. However, the specific timing and patterns of these maternal psychological symptoms during pregnancy that influence the child’s neurodevelopment remain unclear. …”

Table 1_Associations of specific food sources of dietary fat with prostate cancer incidence and mortality: results from a large prospective cohort.docx by Yong-xin Fu (22644743)

“…However, a greater intake of plant-based monounsaturated fatty acids (MUFAs; HR _Q4vs.Q1: 0.67; 95% CI: 0.48–0.94; P_trend = 0.023), plant-based SFAs (HR _Q4vs.Q1:0.65; 95% CI: 0.47–0.91; P_trend = 0.026) and polyunsaturated fatty acids (PUFAs) from fish (HR _Q4vs.Q1: 0.48; 95% CI: 0.48–0.87; P_trend = 0.005) was associated with a decreased PCa mortality in a non-linear dose-response relationships (all P_{non − linearity} < 0.05). …”

Image 2_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.jpeg by Yutong Wu (3130584)

“…As DR severity increased, the levels of three DKD indicators presented a significant upward trend compared to those in the control group, except for Hcy in the PDR subgroup. …”