Table 5_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”

Table 3_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”

Table 6_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Introduction<p>The aging brain shows alterations in microglial function, morphology, and phenotype, reflecting a state of chronic activation. CX3CR1 plays a critical role in regulating microglial chemotaxis, phagocytosis, and activation. …”

Supplementary Material for: Race/Ethnic Differences in In-Hospital Mortality after Acute Ischemic Stroke by Sun P.Y. (20106159)

“…Compared to White men, Black, Hispanic, and API men, and Black women had lower aOR of mortality. The differences in mortality between White and all the other race/ethnic groups combined were most pronounced in 75% White hospitals (aOR 0.80, 0.74-0.87) compared to 50-75% White hospitals (aOR 0.85, 0.79-0.91) and <50% White hospitals (aOR 0.88, 0.81-0.95; interaction effect: p=0.005). …”

Supplementary Material for: Transcapillary PO2 Gradients in Contracting Muscle of Rat Model of Sepsis by figshare admin karger (2628495)

Iron biofortification of <i>Pleurotus eous</i> via substrate supplementation by D. Leena Lavanya (21676675)

“…The results showed that while calcium and boron levels have decreased, a few minerals, including sodium, potassium, phosphorus, magnesium, zinc, and copper, have increased significantly (<i>p</i> < .05). …”

Image 1_The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury.tif by Xuexue Cui (11574637)

“…In the RPE/choroid, the abundance of Actinomyces and Roseburia decreased, and the abundance of Lactobacillus increased significantly after laser injury. …”

Table 1_Exogenous jasmonic acid and salicylic acid enhance selenium uptake and mitigate cadmium accumulation in pak choi (Brassica chinensis L.) grown in selenium-rich, high-cadmiu... by Jin-Ping Chen (6003755)

“…Cd accumulation in shoots decreased by 11.7%-29.3% in JA-containing treatments, with the same combined producing the lowest shoot Cd levels. …”

Table 1_Impact of fasting and refeeding on immune markers, hepatic gene expression, and gut microbiota in geese: insights into metabolic regulation and gut-liver interactions.xlsx by Yi Liu (36759)

“…In this study, biochemical, transcriptome and 16S rRNA sequencing techniques were used to investigate the physiological effects of fasting and refeeding on immune responses, liver gene expression, and gut microbiota composition in geese. Fasting led to a significant reduction in circulating levels of IgA and IFN-γ, while IgG, TNF-α, IL-6, and IL-10 levels remained stable. …”

Supplementary file 1_Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omic... by Rui Hou (161624)

“…</p>Results<p>GCT treatment significantly improved spatial memory and reduced the protein levels of Aβ and proinflammatory factors in APP/PS1 mice. …”

Table 2_Impact of fasting and refeeding on immune markers, hepatic gene expression, and gut microbiota in geese: insights into metabolic regulation and gut-liver interactions.xlsx by Yi Liu (36759)

“…In this study, biochemical, transcriptome and 16S rRNA sequencing techniques were used to investigate the physiological effects of fasting and refeeding on immune responses, liver gene expression, and gut microbiota composition in geese. Fasting led to a significant reduction in circulating levels of IgA and IFN-γ, while IgG, TNF-α, IL-6, and IL-10 levels remained stable. …”

Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023) by figshare admin karger (2628495)

“…Results Pre-pandemic, SO remained stable or declined in children under 12 until 2010: OR5: 0.8-1, p<0.001) but rose significantly afterward (OR5: 1.1-1.2, p<0.001). Children between 12-16 years of age showed a continuous increase, especially boys (boys12-16: OR5: 1.3, girls12-16: OR5: 1.1, p<0.001). …”

Data Sheet 1_Direct economic burden of acute coronary syndromes in the Portuguese National Health Service—facts and trends between 2002 and 2022.pdf by Francisco Madeira (20892980)

“…</p>Conclusion<p>ACS represent a significant direct cost and economic burden for the NHS.…”

Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx by Dongsheng Tang (5526149)

“…</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”

Temporal Regulation of Myopia and Inflammation-Associated Pathways in the Interphotoreceptor Retinoid-Binding Protein Knockout Mouse Model by Shanu Markand (19730205)

“…ANOVA assessed statistical significance, and a <i>p</i> < 0.05 was considered significant.…”

Mitochondria-Derived Reactive Oxygen Species Regulation of Tardigrade Osmobiosis Revealed by Proteomics of Hypsibius exemplaris by Evan R. Stair (17803878)

“…Finally, inhibition of mitochondrial ROS significantly decreases the rate of osmobiote formation suggesting a regulation of osmobiosis through MRC-derived ROS. …”

The quality metrics of 4C-seq data. by Tingting Jiang (169999)

“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”

Image2_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.tif by Chunjie Liu (3437477)

“…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …”

Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis by Yuechu Zhao (20481846)

“…Ferroptosis-related proteins were significantly increased post-MI in Apelin^−/− mice whereas p-AMPK was greatly decreased. …”