Data Sheet 1_Gut microbiota is involved in the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic animals by activation of the TLR4 pathway.pdf by Nathalia Santos Magalhães (14131047)

“…Furthermore, both TLR4 antagonist and TLR4 mutant mice (C3H/HeJ) induced a significant reduction in plasma corticosterone levels in diabetic mice.…”

Image 4_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Table 1_Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars.doc by Xiaohui Sun (520181)

“…<p>Salinity is a major abiotic stress that threatens crop yield and food supply in saline soil areas. …”

Table2_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.docx by Chunjie Liu (3437477)

“…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …”

Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx by Jinghuai Ni (21023477)

“…Objectives<p>Scorpion and Centipede (SC) is an ancient formula of traditional Chinese medicine that is commonly utilized in a range of disorders, and it has been shown to have pharmacological effects on postmenopausal osteoporosis (PMOP). …”

Data Sheet 1_Probiotic administration correlated with reduced diarrheal incidence and improved gut microbiota diversity in young goats.pdf by Mohamed Osman Abdalrahem Essa (21562583)

“…The predominant phyla identified were Pseudomonadota, Bacteroidetes, and Bacillota.Increased levels of Xylanibacter, UCG-055, Bacteroides, and Escherichia-Shigella were noted in healthy treated kids, while Prevotellaceae UG_001 and Proteus decreased.</p>Discussion<p>The findings highlight significant gut microbiota differences between healthy and diarrheal kids, suggesting that modifications in gut microbiota composition could alleviate diarrhea, contributing to preventive and therapeutic strategies for this condition.…”

DataSheet1_Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice.docx by Sayra J. Garcia (19748644)

“…</p>Results<p>In this study, we found that LCN2 deficiency significantly attenuates neuropsychiatric and cutaneous disease in MRL/lpr lupus prone mice, likely by decreasing local infiltration of immune cells into the brain and skin and reducing astrocyte activation in the hippocampus. …”

Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Image1_Metabolomic disorders caused by an imbalance in the gut microbiota are associated with central precocious puberty.tif by Chunjie Liu (3437477)

“…</p>Results<p>The gut microbiota composition in CPP patients was significantly different from that in healthy controls, characterized by an increased abundance of Faecalibacterium and a decreased abundance of Anaerotruncus. …”

Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Image 1_Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.jpeg by Ai-Li Xu (20622440)

“…<p>Doxorubicin (DOX) is a prevalent chemotherapeutic drug for treating several malignancies. …”

Data Sheet 2_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.docx by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Data Sheet 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Table1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.xlsx by Hongling Qin (5557505)

“…To further improve the performance of COSMO-RS, two options were used, i.e., the polynomial expression to correct the COSMO-RS results and the combination of COSMO-RS and machine learning algorithms (eXtreme Gradient Boosting, XGBoost) to develop a hybrid model. The results show that the COSMO-RS with correction can significantly improve the prediction of CO₂ solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …”

Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production by Jacob Hodge (2699521)

“…We aimed to evaluate whether a novel hydrogel-based Bio-Block® platform preserved intrinsic adipose-derived MSC (ASCs) phenotype and secretome compared with conventional systems.…”

Table 1_Association between higher estimated glucose disposal rate and reduced prevalence of hyperuricemia and gout.docx by Pengfei Liu (136115)

“…</p>Conclusion<p>A significant inverse association was observed between eGDR and the prevalence of HUA and gout. …”

Figure 5 from Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment–dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors by Eleonora Y. Khlebus (20814571)

“…Colors of heatmap display gene expression <i>Z</i>-scores that are computed on a gene-by-gene basis: Increased expression (red) and decreased expression (blue). …”

The components of Qili Qiangxin capsule. by Minyan Sun (19751378)

“…Hematoxylin and eosin, Masson, and Picrosirius red staining under a light microscope indicated that QLQX treatment suppressed fibrosis and promoted angiogenesis by decreasing the protein expression levels of proteins related to cardiac remodeling including transforming growth factor-β1, metalloproteinase-9 and α-smooth muscle actin and increasing the expression of tissue inhibitor of matrix metalloproteinase-1 concentration. …”

Single-cell RNA-seq dataset of innate lymphoid cells by Sijie Chen (12510043)

“…Our research, along with others’, indicates a high proportion of LTi cells in the fetal ILC pool, which significantly decreases after birth. …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”