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10881
Table 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10882
Image 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10883
Table 7_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.xlsx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10884
Table 3_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10885
Image 7_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10886
Image 3_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10887
Table 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10888
Image 8_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10889
Image 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10890
Table 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10891
Image 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10892
Image 9_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10893
Image 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10894
Table 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…</p>Results<p>Homozygous, crim1<sup>−/−</sup> larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1<sup>−/−</sup> larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”
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10895
Table 1_Dynamic changes of gut microbiota between the first and second trimester for women with gestational diabetes mellitus and their correlations with BMI: a nested cohort study...
Published 2024“…Inflammation-associated genera like Gemmiger_A_73129 and Enterocloster increased, while Megamonas decreased in overweight or obese GDM women, which was not identified in normal-weight women. …”
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10896
Table 1_Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large...
Published 2025“…Longitudinal changes in bilateral ONSD showed remarkable overlap in both individual and group observations. Patients with improved outcomes exhibited decreasing ONSD trends, whereas those with deterioration displayed increasing trends.…”
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10897
Supplementary file 1_Comparison of morrow procedure and transapical beating-heart septal myectomy in patients with hypertrophic obstructive cardiomyopathy: a systematic review and...
Published 2025“…</p>Objectives<p>To compare the efficacy and safety of surgical myectomy and TABSM in patients with HOCM.</p>Methods<p>A systematic search of PubMed, Web of Science, Cochrane Library, and ScienceDirect (January 2014–May 2025) identified 24 observational studies including 3,732 patients (2,824 surgical myectomy; 908 TABSM). …”
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10898
Image 1_Snowmelt seepage fluxes of dissolved organic matter in forest and grassland – a molecular-level case study from the Hainich Critical Zone Exploratory, Germany.pdf
Published 2024“…This study, conducted at the Hainich Critical Zone Exploratory in Germany, seeks to address a significant gap in understanding the molecular impacts of snowmelt-induced DOM flows and their ability to alter soil ecosystems rapidly. …”
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10899
Imformation.
Published 2025“…Flow cytometry revealed a significant decrease in the apoptosis of HK-2 cells. …”
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10900
DataSheet1_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review...
Published 2024“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO<sub>2</sub> (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO<sub>2</sub> (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”