DataSheet1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Video 1_Progressive encephalomyelitis with rigidity and myoclonus after thymectomy in a woman with myasthenia gravis.mp4 by Lixia Qin (3358520)

“…The patient was treated with intravenous methylprednisolone, oral clonazepam, and tacrolimus, which resulted in significant clinical improvement. A 2-year follow-up demonstrated sustained recovery, accompanied by a decrease in GAD65 antibody titers. …”

DataSheet2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…This study employed a multi-omics approach, integrating single-cell and bulk RNA sequencing from 21 sepsis samples and Escherichia coli-induced sepsis datasets, alongside bioinformatics, machine learning, and experimental validation in a rat model and human peripheral blood. We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Image 2_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…This study employed a multi-omics approach, integrating single-cell and bulk RNA sequencing from 21 sepsis samples and Escherichia coli-induced sepsis datasets, alongside bioinformatics, machine learning, and experimental validation in a rat model and human peripheral blood. We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Table2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Table3_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Supplementary material Figure S3 by Alireza Mani (3341171)

“…For the PD networks (left column), the nodes represent the physiological variables, the edges show significant correlations (p≤Bonferroni-adjusted p-value) between the two nodes, and the edge labels display the mean PD values for no deterioration and deterioration groups along the significantly correlated variable pair axes. …”

Immunoblots analysis of mitophagy-related protein expression. by Michael O. Isei (20500908)

“…Densitometry quantification of the respective mitophagy receptors show that FKBP8 expression was significantly reduced in cells expressing EC and EM compared to T4 <b>(E)</b>, while BNIP3 and FUNDC1 receptor levels decreased significantly in all groups <b>(F, G)</b>. …”

Table 1_Gamma knife radiosurgery for cerebral cavernous malformations: biologically effective dose predicts therapeutic outcomes.docx by Xiaoman Shi (12587770)

“…</p>Conclusion<p>GKRS significantly reduced hemorrhage risk and promoted lesion regression in CCMs. …”

Supplementary material Figure S2 by Alireza Mani (3341171)

“…For the PD networks (left column), the nodes represent the physiological variables, the edges show significant correlations (p ≤ Bonferroni-adjusted p-value) between the two nodes, and the edge labels display the mean PD values for survivors and non-survivor groups along the significantly correlated variable pair axes. …”

Table_1_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …”

Table_3_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …”

Data_Sheet_1_The total joint arthroplasty care patterns in China during the COVID-19 pandemic: a multicenter cohort study.PDF by Tianyi Zhang (87298)

“…No significant changes were observed in the proportion of hospitalizations for TJA. …”

Table 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.docx by Bo Peng (273834)

“…</p>Results<p>From 1990 to 2021, the incidence, prevalence, mortality, and DALYs of MND in China, the United States, and globally showed significant increases, with the largest increase observed in mortality (China +126%, USA +118%, global +156%). …”

Supplementary file 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.doc... by Bo Peng (273834)

“…</p>Results<p>From 1990 to 2021, the incidence, prevalence, mortality, and DALYs of MND in China, the United States, and globally showed significant increases, with the largest increase observed in mortality (China +126%, USA +118%, global +156%). …”

Table_2_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …”

Presentation 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.pptx by Bo Peng (273834)

“…</p>Results<p>From 1990 to 2021, the incidence, prevalence, mortality, and DALYs of MND in China, the United States, and globally showed significant increases, with the largest increase observed in mortality (China +126%, USA +118%, global +156%). …”

Table_4_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …”

Image5_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg by Jiayu Ding (12005975)

“…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …”