Supplementary file 1_Global, regional, and national burdens of MDR-TB attributable to smoking from 1990 to 2021 with a prediction from 2022 to 2050.docx حسب Du Dan (22274296)

"…Objective<p>The aim was to offer a comprehensive epidemiological assessment of the global prevalence and the smoking-related Multidrug-resistant tuberculosis (MDR-TB) disease burden from 1990 to 2021 and to forecast the trends in smoking burden over three decades.</p>Methods<p>We compared the burden of smoking-related MDR-TB and temporal trends by gender, age, socio-demographic index (SDI), region, and country. …"

Table1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Video 2_Progressive encephalomyelitis with rigidity and myoclonus after thymectomy in a woman with myasthenia gravis.mp4 حسب Lixia Qin (3358520)

"…The patient was treated with intravenous methylprednisolone, oral clonazepam, and tacrolimus, which resulted in significant clinical improvement. A 2-year follow-up demonstrated sustained recovery, accompanied by a decrease in GAD65 antibody titers. …"

Data Sheet 2_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.docx حسب Imke L. Jansen (22089944)

"…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …"

Data Sheet 1_Non-stationary response of Pacific saury (Cololabis saira) in the northwestern Pacific to climate variability.docx حسب Chang Cao (2592700)

"…The dynamics of Pacific saury from 1970 to 2021 could be divided into four periods: the 1970s and 1980s when the Siberian High and the intensification of the East Asian winter monsoon drove down the water temperature, providing a suitable habitat and resulting in an increase in resource abundance; In the 1990s, the rise in temperature led to a reduction in resource abundance; At the beginning of the 21st century, the enhancement of the Siberian High brought about a suitable habitat, and the resource abundance showed a significant increase; The unfavorable high water temperature environment in the 2010s caused the resource abundance to decrease once again. …"

Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic. حسب Ghattas Bisharat (20706928)

"…(b) Change in activity across sessions per tracked cell in response to 40, 60, and 70 dB white noise. We found a negative slope in most cells especially for mid-intensities, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for 40 dB <i>p</i> = 0.36, for 60 dB <i>p</i> = 9.3 × 10⁻¹², and for 70 dB <i>p</i> = 0.00750). …"

DataSheet1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Exposure to environments with different norms changes participants’ behavior. حسب Claire Lugrin (21156528)

"…Each participant faced one of four environments. We varied the type of norm that was manipulated (descriptive versus prescriptive norms) and the direction of the change (increased or decreased prosociality). …"

Video 1_Progressive encephalomyelitis with rigidity and myoclonus after thymectomy in a woman with myasthenia gravis.mp4 حسب Lixia Qin (3358520)

"…The patient was treated with intravenous methylprednisolone, oral clonazepam, and tacrolimus, which resulted in significant clinical improvement. A 2-year follow-up demonstrated sustained recovery, accompanied by a decrease in GAD65 antibody titers. …"

DataSheet2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg حسب Tianle Cheng (20788417)

"…This study employed a multi-omics approach, integrating single-cell and bulk RNA sequencing from 21 sepsis samples and Escherichia coli-induced sepsis datasets, alongside bioinformatics, machine learning, and experimental validation in a rat model and human peripheral blood. We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …"

Image 2_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg حسب Tianle Cheng (20788417)

"…This study employed a multi-omics approach, integrating single-cell and bulk RNA sequencing from 21 sepsis samples and Escherichia coli-induced sepsis datasets, alongside bioinformatics, machine learning, and experimental validation in a rat model and human peripheral blood. We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …"

Table2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Table3_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Table_1_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... حسب Kexin Zhang (301752)

"…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …"

Table_3_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... حسب Kexin Zhang (301752)

"…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …"

Data_Sheet_1_The total joint arthroplasty care patterns in China during the COVID-19 pandemic: a multicenter cohort study.PDF حسب Tianyi Zhang (87298)

"…No significant changes were observed in the proportion of hospitalizations for TJA. …"

Table 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.docx حسب Bo Peng (273834)

"…</p>Results<p>From 1990 to 2021, the incidence, prevalence, mortality, and DALYs of MND in China, the United States, and globally showed significant increases, with the largest increase observed in mortality (China +126%, USA +118%, global +156%). …"

Supplementary file 1_Comparative analysis of trends in the burden of motor neuron disease in China, the United States, and globally from 1990 to 2021: projections for 2022–2041.doc... حسب Bo Peng (273834)

"…</p>Results<p>From 1990 to 2021, the incidence, prevalence, mortality, and DALYs of MND in China, the United States, and globally showed significant increases, with the largest increase observed in mortality (China +126%, USA +118%, global +156%). …"

Table_2_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... حسب Kexin Zhang (301752)

"…Fall risk was evaluated with the fall risk assessment tool.</p>Results<p>Significant differences in age, weight, education, smoking status, alcohol consumption, cognitive impairment, malnutrition, daily living abilities, depressive state, baPWV, ABI (all p < 0.001), systolic pressure, heart rate, cardiac stroke volume, and systemic vascular resistance were observed among the three groups (p = 0.011, p = 0.035, p = 0.005, p = 0.016). …"