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9601
Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx
Published 2025“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”
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9602
Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx
Published 2025“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”
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9603
Data Sheet 1_A study on the spatial distribution of life expectancy and its air pollution factors in China based on geographically weighted regression.xls
Published 2025“…</p>Results<p>The findings revealed that in 2020, life expectancy in China exhibited a distinct east-to-west decreasing trend, demonstrating significant spatial autocorrelation that was predominantly characterized by two aggregation patterns: high-high and low-low clusters. …”
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9604
Table 1_Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.docx
Published 2025“…Multivariate smooth splines analysis revealed a nonlinear relationship (P for nonlinearity < 0.05), with the curve slope decreasing as MAP exceeded 103.23 mmHg. …”
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9605
<b>Keystone taxa and microbial network complexity, rather than diversity, sustain soil multifunctionality along an elevational gradient in a subtropical karst mountain</b>
Published 2025“…Notably, the positive effects of network complexity and keystone taxa abundance on soil EMF decreased with increasing threshold levels of EMF, yet keystone taxa abundance retained a significant positive effect even at the highest threshold (75%). …”
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9606
Video 1_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4
Published 2024“…The patient was then administered a combination of anlotinib and tislelizumab. After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”
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9607
Video 2_Anlotinib combined with tislelizumab in the treatment of primary small cell neuroendocrine carcinoma of the prostate: a case report and literature review.mp4
Published 2024“…The patient was then administered a combination of anlotinib and tislelizumab. After treatment, the patient’s symptoms were controlled, tumor marker levels decreased, and imaging showed significant improvement. …”
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9608
Table 3_Comparative performance evaluation of large language models in answering esophageal cancer-related questions: a multi-model assessment study.xlsx
Published 2025“…Retesting showed improvements in overall quality, yet some responses showed decreased completeness and relevance.</p>Conclusion<p>Large language models have considerable potential in answering questions about esophageal cancer, with significant differences in completeness. …”
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9609
Table 1_Impact of the Yangtze River on Sediment source-to-sink processes in estuarine bays: a study of the Oujiang River Estuary, SE China.docx
Published 2025“…Notably, we observed a gradual increase in the proportions of illite and smectite from the upstream to the estuary, while kaolinite decreased accordingly. …”
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9610
Table 2_Comparative performance evaluation of large language models in answering esophageal cancer-related questions: a multi-model assessment study.xlsx
Published 2025“…Retesting showed improvements in overall quality, yet some responses showed decreased completeness and relevance.</p>Conclusion<p>Large language models have considerable potential in answering questions about esophageal cancer, with significant differences in completeness. …”
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9611
Table 1_Comparative performance evaluation of large language models in answering esophageal cancer-related questions: a multi-model assessment study.xlsx
Published 2025“…Retesting showed improvements in overall quality, yet some responses showed decreased completeness and relevance.</p>Conclusion<p>Large language models have considerable potential in answering questions about esophageal cancer, with significant differences in completeness. …”
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9612
Table 1_Effect of pain-relief nursing on activities of daily living in patients following hip arthroplasty: a systematic review and meta-analysis.docx
Published 2025“…Background<p>Discomfort and reduced physical function can often be significant after hip arthroplasty procedures, especially in older adults. …”
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9613
Table 1_A cohort-based assessment of drug use trends during the COVID-19 pandemic: relationship with mood and sociodemographic factors in Brazil.docx
Published 2025“…<p>The COVID-19 pandemic has brought significant challenges, including severe psychological consequences, especially for vulnerable individuals, such as those with substance use disorders. …”
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9614
Data Sheet 1_Causal relationship between gut microbiota and diabetic neuropathy: a Mendelian randomization and 16S rRNA sequencing analysis.zip
Published 2025“…Objectives<p>Evidence suggests a link between gut microbiota and diabetes mellitus, yet the specific role in diabetic peripheral neuropathy (DPN) remains elusive. …”
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9615
Data Sheet 1_Assessing the impact of climate change on the potential distribution of Keteleeria evelyniana Mast. in southwest China: a Maxent modeling approach.docx
Published 2025“…In various future climate scenarios, the suitable areas for K. evelyniana gradually decreased, with a maximum reduction of 33%. Simultaneously, the centroids of these areas are expected to migrate northward by up to 33 km. …”
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9616
Data Sheet 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.pdf
Published 2025“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”
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9617
Table 1_Impact of different 3D regions of interest on quantifying dynamic lumbar vertebral microstructure in ovariectomized rats—a micro-CT study.doc
Published 2025“…The BMD and BV/TV also showed a significant reduction at 24 weeks postoperatively compared with those at 12 weeks postoperatively. …”
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9618
Table 1_Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study.docx
Published 2025“…Involvement of human serum albumin (HSA) could be a possible reason behind the inconsistency. We prospectively examined the associations between urinary enterolignans and the risk of overall and cause-specific mortality among US adults and evaluated the impact of adjusting for HSA by comparing the results before and after its inclusion as a covariate.…”
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9619
Table 1_Hemoglobin and clinical outcomes of in-hospital patients with severe acute exacerbation of chronic obstructive pulmonary disease: a multicenter cohort study.docx
Published 2025“…The cohort identified a significant association between anemia and adverse outcomes when compared to the normal group (5.20% vs. 2.80%, p < 0.001), including In-hospital mortality (1.12% vs. 0.29%, p < 0.001), invasive ventilation (2.12% vs. 1.19%, p = 0.001), ICU admission (4.24% vs. 2.41%, p < 0.001). …”
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9620
DataSheet1_Hypoglycemic activity of Garcinia mangostana L. extracts on diabetes rodent models: A systematic review and network meta-analysis.docx
Published 2024“…Background<p>Diabetes mellitus is a significant global health issue, and alternative treatments from natural products like Garcinia mangostana L. …”