Detection of Tn-antigen in breast and prostate cancer models by VVL-labeled red dye-doped nanoparticles by Alejandra Verhassel (19823895)

“…<p><b>Aim:</b> Fluorescence detection of breast and prostate cancer cells expressing Tn-antigen, a tumor marker, with <i>Vicia villosa</i> lectin (VVL)-labeled nanoparticles.…”

Image 1_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.tiff by Ru Chen (186859)

“…Regionally, both mortality rates and DALYs significantly decrease with increasing SDI. Sub-Saharan Africa and South Asia have high levels of incidence and prevalence. …”

Table 1_Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of dise... by Lu-yao Cheng (20687651)

“…The risk factors, which included unsafe sex and smoke, significantly varied by region. The global ASIR exhibited a downward trend from 2021 to 2035.…”

Table 2_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.docx by Ru Chen (186859)

“…Regionally, both mortality rates and DALYs significantly decrease with increasing SDI. Sub-Saharan Africa and South Asia have high levels of incidence and prevalence. …”

Thermogenetic activation in male flies. by Joseph D. Jones (13883524)

“…<b>(D)</b> Box plots of nighttime sleep bout duration for flies presented in A. Two-way repeated measures ANOVA followed by Sidak’s multiple comparisons revealed that control and most FBS lines show a significant decrease in nighttime sleep bout duration between 22 °C and 31 °C, and 4 sleep-promoting FBS lines show no difference between 22 and 31 °C (FBS42, FBS53, FBS81, and FBS84) while FBS45 and FBS68 show an increase in nighttime sleep bout duration at 31 °C. …”

Supplementary file 1_Meta-analysis of Xiaoyao formula as an adjuvant therapy for treating postpartum depression.docx by Jing Liu (38537)

“…Additionally, XYF as an adjuvant therapy also significantly decreased Hamilton Depression Scale scores (standard mean difference [SMD] -1.69; 95% CI -2.37 to -1.01).…”

Supplementary file 2_Meta-analysis of Xiaoyao formula as an adjuvant therapy for treating postpartum depression.docx by Jing Liu (38537)

“…Additionally, XYF as an adjuvant therapy also significantly decreased Hamilton Depression Scale scores (standard mean difference [SMD] -1.69; 95% CI -2.37 to -1.01).…”

Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Table 3_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx by Ruonan Qiang (22753394)

“…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. …”

Table 1_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx by Ruonan Qiang (22753394)

“…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. …”

Table 2_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx by Ruonan Qiang (22753394)

“…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. …”

Effect of <i>INS-19</i> and <i>INS-20</i> gene knockout on the growth of <i>Cryptosporidium parvum</i>. by Yue Huang (285485)

“…At the peak of infection, mice infected with the <i>Δins-19</i> line showed a threefold decrease in fecal luciferase activity compared to those infected with the IId-GFP line, while those infected with the <i>Δins-20</i> line showed a 6-27-fold decrease in fecal luciferase activity. …”

AjMLKL is involved in 10⁸ CFU/mL AJ01 induced lytic coelomocyte death independent on its phosphorylation. by Kaiyu Chen (11691918)

“…Coelomocyte viability was significantly increased (L), and coelomocytes plasma membrane disruption (M) and the percentage of Annexin V+/PI+ coelomocytes significantly decreased (N). …”

Data Sheet 1_The impact of gradient variable temperature fermentation on the quality of cigar tobacco leaves.pdf by Qianying Zhang (2391760)

“…A total of 17 chemicals significantly decreased and six increased, and the decline of microbial populations persisted. …”

Supplementary file 1_Comparison of the ruminal microbiome responses of temperate and tropically adapted beef steers to dietary supplementation with monensin.docx by Ross L. Thorn (22688840)

“…The qPCR assays indicated significantly lower ruminal methanogen contents (mcrA gene; p < 0.01) and a reduced methanogen/prokaryote ratio (MPR; p < 0.001) in monensin-fed steers compared with the control. …”

Data Sheet 1_Genomic and immune profiling of prognostic risk groups in IgM gammopathy reveals novel biomarkers beyond MYD88 L265P.docx by David F. Moreno (5597948)

“…</p>Results<p>We observed that low-risk patients were only characterized by the presence of MYD88 L265P, while intermediate- and high-risk groups harbored additional mutations on CXCR4, KMT2D, ARID1A and EP300. Regarding the mRNA expression analyses, we found an increased proportion of myeloid cells in the low-risk group, with monocytes having a significant decrease in low versus high-risk patients. …”

Supplementary file 1_The effect of development on cortical auditory evoked potentials in normal hearing listeners and cochlear implant users.docx by Eun Kyung Jeon (2032222)

“…</p>Results<p>Both onset and ACC responses were present across groups, with P1 latency decreasing significantly with age in NH and CI listeners. …”

Table 1_Quantifying the effect of air pollution and temperature on hospitalization costs for chronic lower respiratory diseases.docx by Huanhuan Jia (2546878)

“…With respect to temperature, the hospitalization costs of people aged 60 and above increased by 8.70% on low-temperature days, and the exposure response ratio from lag day 0 to lag day 5 showed a statistically significant gradual decrease. Additionally, on lag days 5 and 11, the hospitalization costs of female patients with CLRDs increased by 3.35 and 3.92%, respectively.…”

Table 2_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”