Neutrophil Superoxide anion production, Heat map for gene expression from neutrophils of CGD patients, and PCA plot for genome-wide gene expression. by Daniel R. Ambruso (12042605)

“…Heat map</b> showing changes for all significant genes between off IFN-γ and 10-12 hours after the 1st and 4th dose (50 µg/m²) of the cytokine given on a routine schedule noted in Methods. …”

Representative Western blots for proteins from specific gene groups, nitric oxide production, and NETs formation. by Daniel R. Ambruso (12042605)

PbPP6 disruption impairs the cGMP-PKG-Ca²⁺ signaling pathway. by Yonghui Feng (12227596)

The sexual stage phenotype of <i>pbpp6</i> gene knockout clones. by Yonghui Feng (12227596)

Flow cytometry measurement of CD11b, F-actin expression and content, and MHC Class II antigen expression of neutrophils from patients with CGD. by Daniel R. Ambruso (12042605)

Phenotype analysis of PbPP6-GFP parasites. by Yonghui Feng (12227596)

Sequence composition analysis identifies distinct A + U and C + G base frequencies within subregions of mRNA transcripts – with effects on protein coding potential. by Benjamin S. Pickard (21276556)

Frequency trajectories of iSNVs that fluctuated (Top) and their positions on the genome (Bottom) (patients A-I). by Lele Zhao (532080)

Addressing Imbalanced Classification Problems in Drug Discovery and Development Using Random Forest, Support Vector Machine, AutoGluon-Tabular, and H2O AutoML by Ayush Garg (21090944)

“…The important findings of our studies are as follows: (i) there is no effect of threshold optimization on ranking metrics such as AUC and AUPR, but AUC and AUPR get affected by class-weighting and SMOTTomek; (ii) for ML methods RF and SVM, significant percentage improvement up to 375, 33.33, and 450 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy, which are suitable for performance evaluation of imbalanced data sets; (iii) for AutoML libraries AutoGluon-Tabular and H2O AutoML, significant percentage improvement up to 383.33, 37.25, and 533.33 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy; (iv) the general pattern of percentage improvement in balanced accuracy is that the percentage improvement increases when the class ratio is systematically decreased from 0.5 to 0.1; in the case of F1 score and MCC, maximum improvement is achieved at the class ratio of 0.3; (v) for both ML and AutoML with balancing, it is observed that any individual class-balancing technique does not outperform all other methods on a significantly higher number of data sets based on F1 score; (vi) the three external balancing techniques combined outperformed the internal balancing methods of the ML and AutoML; (vii) AutoML tools perform as good as the ML models and in some cases perform even better for handling imbalanced classification when applied with imbalance handling techniques. …”

Various stereological parameters characterizing lung parenchyma and AEII before, during and after alveolarization as well as in adults. by Julia Hüttmann (22656283)

“…PLoS One. 2024 Mar 14;19(3):e029. b) The total number of alveolar epithelial cells type II (N(AEII, lung)) shows a significant increase after the end of bulk alveolarization and in adults compared to 3 days old rats. c) During alveolarization the number of AEII per mm² alveolar surface (N(AEII, lung)/S(alveoli, lung)) decreases continuously reaching the significant lowest values in adults. d) The number of AEII related to lung volume decreases continuously during alveolarization. …”

PRMT5 regulates alternative splicing landscape under hypoxia. by Srinivas Abhishek Mutnuru (22513457)

“…<p><b>A)</b> Pie chart showing distribution of different types of significant AS events (FDR < 0.05) in shCTRL vs. shPRMT5 MDA-MB-231 cells under hypoxia. …”

The atrium and ventricle exhibit different tissue dynamics during morphogenesis. by Juliana Sánchez-Posada (20636677)

“…Total endocardial volume decreases after 58 hpf (D), driven by a reduction in endocardial tissue in both the atrium and ventricle (E); 34–36 hpf: <i>n</i> = 9; 48–50 hpf: <i>n</i> = 10; 58–60 hpf: <i>n</i> = 8; 72–74 hpf: <i>n</i> = 10. …”

Participants’ Mean Blood Glucose. by Giti Azim (20940548)

“…Total cholesterol and blood glucose were the outcome variables for this study; simple and multiple linear regression was performed to find the associated factors for the outcome variables using a designed-based modeling incorporating sampling techniques and weights. …”

Participants’ Mean Total Cholesterol. by Giti Azim (20940548)

“…Total cholesterol and blood glucose were the outcome variables for this study; simple and multiple linear regression was performed to find the associated factors for the outcome variables using a designed-based modeling incorporating sampling techniques and weights. …”

Data file without outliers. by Helena Wallin (6103205)

“…At follow-up, the increase in KYN and KYN/TRP was related to a decrease in ExCap in CKD 2–3. After adjusting for GFR, increase in KYN/TRP remained an independent significant predictor of a decline in ExCap in CKD 2–3.…”

Δ<i>guaA,</i> a mutant that lacks a cytochrome P450 monooxygenase, does not grow on guaiacol. by Claudia Castro (585495)

“…</i> Wildtype (solid black line) showed growth (OD_{600 nm}) and guaiacol degradation (blue line) beginning 24 hours post-incubation. Meanwhile, Δ<i><i>guaA</i></i> (dashed black line) never demonstrated an increase in OD_{600 nm} or significant guaiacol decrease (<i><i>n</i> </i>= 12)<i>.…”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”