EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1 by Salvador García-Carmona (20580797)

“…The aim of this study was to assess the changes that genetic material can exhibit and their impact on the production of proteins involved in the disease.</p> <p>We found a significant effect on genes that play roles in inflammation and detoxification processes in the body. …”

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study by figshare admin karger (2628495)

“…In a univariate analysis, multi-domain recognition decreases the probability of remission[HR, 0.38 (95% CI, 0.16-0.87), P = 0.022]. …”

Table2_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Data Sheet 1_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.pdf by Renshengjie Zhao (22459771)

“…Using siRNA gene knockdown technology, we suppressed NRIR and RSAD2 expression in M1 macrophages derived from THP-1 cells. …”

Table1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Data_Sheet_1_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Numerical data and gene lists for all graphs. by Hilary T. Brewis (11798006)

“…To explore this possibility, we generated mRNA transcript profiles for wild-type, <i>htz1</i>Δ, <i>swr1</i>Δ, and <i>htz1</i>Δ<i>swr1</i>Δ mutants before and after exposure to hydroxyurea (HU), which induces DNA replication stress. …”

DESeq output data for all comparisons. by Hilary T. Brewis (11798006)

“…To explore this possibility, we generated mRNA transcript profiles for wild-type, <i>htz1</i>Δ, <i>swr1</i>Δ, and <i>htz1</i>Δ<i>swr1</i>Δ mutants before and after exposure to hydroxyurea (HU), which induces DNA replication stress. …”

Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx by Renshengjie Zhao (22459771)

“…Using siRNA gene knockdown technology, we suppressed NRIR and RSAD2 expression in M1 macrophages derived from THP-1 cells. …”

Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Evening Micro-Sprinkler Pavement Cooling / Riego Microaspersor Vespertino para Pavimentos by Ricardo Riveros (22484566)

“…<p dir="ltr"><b>Abstract:</b><br>We propose a scalable, low-cost intervention to reduce urban heat on major roads and highways by applying a controlled micro-sprinkling of water during late-evening hours, when solar radiation is low and vehicle traffic has decreased. …”

Replication package for "Measuring trade costs and analyzing the determinants of trade growth between Cambodia and major trading partners: 1993-2019" by Borin Keo (20919743)

“…</p><p dir="ltr"><b>Key findings: </b>We find that Cambodia's average trade costs decreased by 35.43% between 1993 and 2019. …”

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel by Satoshi Kaneda (571209)

“…In Exp.S1.1, under continuous extraction, efficiency increased from 2 h to 5 h but was greater over 2 h than over 24 h using different soil samples in Exp. …”

Data Sheet 1_Real-time evaluation of antibacterial efficacy using bioluminescent assays for Pseudomonas aeruginosa and Staphylococcus aureus.pdf by Manali Patil (22142128)

“…Treatment with cefotaxime resulted in a significant reduction of the bioluminescent signal in P. aeruginosa compared to untreated controls, while doxycycline induced a delayed growth curve. …”

Efficacy of Low-Dose Naltrexone in Treating Patients with Fibromyalgia: systematic Review and Meta-Analysis by Abiodun Ologunowa (21343002)

“…This systematic review and meta-analysis aimed to evaluate the efficacy of LDN for fibromyalgia. We systematically searched electronic databases and gray literature from inception to May 2024. …”

Species removal dampens the scale dependency of ecological determinism and stochasticity in rocky intertidal communities [dataset and codes] by Nelson Valdivia (600515)

“…However, the responses of both processes to the loss of foundation species, which strongly influence community dynamics across spatial scales, are unclear. We experimentally examined how spatial extent and foundation species removal affect rocky-intertidal community dynamics over three years in eight field sites spanning ~1000 km along the southeastern Pacific. …”

Table 1_Organic and inorganic fertilizers modulate the response of the soil microbiome to salinity stress.docx by Halima Malal (21570602)

“…Furthermore, NPK fertilization increased bacterial network complexity but decreased its stability. This study underscores the significance of employing vermicompost to improve the health of saline soils. …”