Image 1_Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study.pdf by Kaylie I. Kirkwood-Donelson (19697360)

“…Additionally, we found that ER treatment decreased cellular levels of NAD+/NADP+, carnitines and glutamine/glutamate in both cells, suggesting significant oxidative stress, decrease in energy production, and cellular and mitochondrial disfunctions, leading to cell death.…”

DataSheet1_The gut microbiota changed by ketogenic diets contribute to glucose intolerance rather than lipid accumulation.docx by Wei Li (7081)

“…Following a 2-week intervention with KDs, mice fed on KD1 displayed symptoms related to obesity, whereas KD2-fed mice exhibited a decrease in body weight but had severe hepatic lipid accumulation and abnormal fatty acid metabolism, while both KDs led to significant glucose intolerance. …”

Data Sheet 1_Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study.xlsx by Kaylie I. Kirkwood-Donelson (19697360)

“…Additionally, we found that ER treatment decreased cellular levels of NAD+/NADP+, carnitines and glutamine/glutamate in both cells, suggesting significant oxidative stress, decrease in energy production, and cellular and mitochondrial disfunctions, leading to cell death.…”

The impact of refractive error correction on health-related quality of life in nursing home residents in Armenia by Aida Giloyan (16826909)

“…Those who had not corrected their vision reported no significant improvement in both PHC and MHC. There were no significant differences in baseline to follow-up mean change scores for PHC and MHC between those who corrected their vision and those who had not.…”

Data Sheet 1_Public perception of COVID-19 in Saudi Arabia during the Omicron wave: recommendations for policy improvement.pdf by Mohammed J. Almalki (11808158)

“…Multivariate logistic regression analysis indicated that anxiety about COVID-19 (AOR = 1.23, 95% CI: 1.15–1.32) and education level (AOR = 1.58, 95% CI: 1.11–2.25) were significant predictors of respondents’ expectations of increases or decreases in COVID-19 cases (p < 0.05). …”

Parallel bond model. by Yanan Sun (316649)

“…Hence, the effect of microcracking on macrocracking under freeze-thaw cycling conditions is analysed by means of a combination of acoustic emission tests and numerical simulations. …”

Table 1_Retinal assessment in 143 patients with white matter lesions: the potential of OCTA as an evaluation tool.docx by Dong Zhang (73558)

“…Data following a normal distribution are presented as means, while non-normally distributed data are reported as medians. …”

Meso-parameters of numerical simulation. by Yanan Sun (316649)

“…Hence, the effect of microcracking on macrocracking under freeze-thaw cycling conditions is analysed by means of a combination of acoustic emission tests and numerical simulations. …”

The simulated freeze-thaw cycle process. by Yanan Sun (316649)

“…Hence, the effect of microcracking on macrocracking under freeze-thaw cycling conditions is analysed by means of a combination of acoustic emission tests and numerical simulations. …”

Table2_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Image1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Table4_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Presentation 1_Identification and validation of lactate-related gene signatures in endometriosis for clinical evaluation and immune characterization by WGCNA and machine learning.p... by Jixin Li (5801207)

“…Additionally, we conducted immune-related analysis in endometriosis and identified small molecule compounds targeting core LR-DEGs.…”

DataSheet1_The harmful effect of ankylosing spondylitis on diabetes mellitus: new evidence from the Mendelian randomization analysis.pdf by Zheng Ren (1766506)

“…To synthesize the results of the MR analyses, we applied meta-analysis techniques using either a fixed or random effects model. …”

Table5_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Image2_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Table1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data Sheet 1_Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers.docx by Sergio Sánchez-García (16862127)

“…We found reduced levels in deceased patients when compared to mild or severe patients, concomitant with a decrease in the LXA₄ biosynthetic pathway and an increase in its degradation pathway. …”

Supplementary file 1_Analysis of gender- and age-stratified asthma burden: forecasting prevalence trends in 2030.docx by Zhenzhen Pan (2637463)

“…Furthermore, we examined the main risk factors contributing to asthma. …”

Table3_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”