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linear decrease » linear increase (Expand Search)
teer decrease » greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
linear decrease » linear increase (Expand Search)
teer decrease » greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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7481
Metrics formula [24].
Published 2025“…Results demonstrate that the developed appraoch is highly accurate and significantly faster than manual classification, which can dramatically decrease software development time and cost.…”
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7482
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7483
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
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7484
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
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7485
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
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7486
RSA results across a broader frequency band (0.1–150 Hz).
Published 2025“…<p><b>(A)</b> For the translation epochs from good trials, the similarity of Same Context was significantly greater than the similarity of Different Context in HC. …”
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7487
Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria...
Published 2025“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”
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7488
Molecular Logic Gate for Sensing pH/Peroxynitrite with Potential Applications in Cisplatin Treatment
Published 2024“…With this probe, the significant roles of pH and ONOO<sup>–</sup> in cisplatin treatment are disclosed, in which the cell account shows a dramatic reduction accompanied by decreased pH and upregulated ONOO<sup>–</sup> levels. …”
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7489
Primer pairs for RT-qPCR.
Published 2025“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”
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7490
RT-qPCR data tables.
Published 2025“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”
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7491
Supplementary Material for: Trends in the Incidence of Rare Eyelid Malignancies: A SEER-Based Study (2000–2021)
Published 2025“…For SGC; ARIMA (0,0,0) model demonstrated a decline in IR in 2011 (IR = 0.0192), increase until 2019, then decrease in 2021 (IR = 0.0246), with a predicted 10-year decrease to 0.026 (95% PI: 0.019–0.032). …”
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7492
Table 1_Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, paralle...
Published 2025“…Furthermore, a medication review decreased the mean number of active ingredients by ~9% in the intervention group compared to the control group.…”
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7493
Citation patterns of Cochrane Reviews and other systematic reviews: a bibliometric analysis
Published 2025“…The time window in which systematic reviews received citations has been progressively decreasing, possibly indicating a trend toward quicker recognition and uptake of these reviews within the academic community. …”
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7494
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7495
Minimal data set.
Published 2025“…This effect might be attributed to decreased resuscitation volumes rather than the type of fluid.…”
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7496
Basic features of microtopography.
Published 2025“…The results showed that: the difference of shallow soil moisture in different microtopographies on a slope surface was not significant, the difference of deep soil moisture was significant, and the soil moisture overuse was the largest in the gully (GU), amounting to 386.36 mm, and the smallest in the ephemeral gully (EG) (131.02 mm); the GU, the sink hole (SH), and the scarp (SC) showed a trend of decreasing and then increasing with the increase of soil depth, and the platform (PL) has little overall trend of change in soil moisture with the increase of soil depth, and the soil moisture of US and EG shows the trend of “decreasing-then increasing-then decreasing” with the increase of soil depth. …”
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7497
Soil bulk density of different microtopographies.
Published 2025“…The results showed that: the difference of shallow soil moisture in different microtopographies on a slope surface was not significant, the difference of deep soil moisture was significant, and the soil moisture overuse was the largest in the gully (GU), amounting to 386.36 mm, and the smallest in the ephemeral gully (EG) (131.02 mm); the GU, the sink hole (SH), and the scarp (SC) showed a trend of decreasing and then increasing with the increase of soil depth, and the platform (PL) has little overall trend of change in soil moisture with the increase of soil depth, and the soil moisture of US and EG shows the trend of “decreasing-then increasing-then decreasing” with the increase of soil depth. …”
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7498
Distribution of study areas.
Published 2024“…(main findings) The results show the following: (1) the primary term of government innovation preferences has a positive effect on the ecological resilience of resource-based cities, and the secondary term has a negative effect, with a decreasing marginal effect. …”
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7499
Descriptive statistics of variables.
Published 2024“…(main findings) The results show the following: (1) the primary term of government innovation preferences has a positive effect on the ecological resilience of resource-based cities, and the secondary term has a negative effect, with a decreasing marginal effect. …”
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7500
Code.
Published 2024“…(main findings) The results show the following: (1) the primary term of government innovation preferences has a positive effect on the ecological resilience of resource-based cities, and the secondary term has a negative effect, with a decreasing marginal effect. …”