Table 6_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.docx by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of... by Long Chen (315739)

“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1 by Salvador García-Carmona (20580797)

“…The aim of this study was to assess the changes that genetic material can exhibit and their impact on the production of proteins involved in the disease.</p> <p>We found a significant effect on genes that play roles in inflammation and detoxification processes in the body. …”

Image 1_Caffeine on the mind: EEG and cardiovascular signatures of cortical arousal revealed by wearable sensors and machine learning—a pilot study on a male group.jpeg by Shabbir Chowdhury (22246345)

“…Although systolic and diastolic BP showed a non-significant upward trend, HR decreased significantly after caffeine intake (77 ± 5.3 bpm to 72 ± 2.5 bpm, p = 0.027). …”

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. by Andrew B. Harvey (21587431)

“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study by figshare admin karger (2628495)

“…In a univariate analysis, multi-domain recognition decreases the probability of remission[HR, 0.38 (95% CI, 0.16-0.87), P = 0.022]. …”

Table2_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Data Sheet 1_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.pdf by Renshengjie Zhao (22459771)

“…Using siRNA gene knockdown technology, we suppressed NRIR and RSAD2 expression in M1 macrophages derived from THP-1 cells. …”

Table1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Data_Sheet_1_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Numerical data and gene lists for all graphs. by Hilary T. Brewis (11798006)

“…To explore this possibility, we generated mRNA transcript profiles for wild-type, <i>htz1</i>Δ, <i>swr1</i>Δ, and <i>htz1</i>Δ<i>swr1</i>Δ mutants before and after exposure to hydroxyurea (HU), which induces DNA replication stress. …”

DESeq output data for all comparisons. by Hilary T. Brewis (11798006)

“…To explore this possibility, we generated mRNA transcript profiles for wild-type, <i>htz1</i>Δ, <i>swr1</i>Δ, and <i>htz1</i>Δ<i>swr1</i>Δ mutants before and after exposure to hydroxyurea (HU), which induces DNA replication stress. …”

Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx by Renshengjie Zhao (22459771)

“…Using siRNA gene knockdown technology, we suppressed NRIR and RSAD2 expression in M1 macrophages derived from THP-1 cells. …”

 'Plan-B':  Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes by marion delphin (13249479)

“…</p><p dir="ltr"><b>Methods:</b> We solicited feedback from individuals with lived experience and/or professionals in the HBV field, reaching out through social media, conferences, professional networks. …”

Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis... by Juan Tang (437969)

“…</p>Methods<p>From 1990 to 2019, we employed the Global Burden of Disease Study (GBD) Results Tool in conjunction with an age-period-cohort model. …”

Evening Micro-Sprinkler Pavement Cooling / Riego Microaspersor Vespertino para Pavimentos by Ricardo Riveros (22484566)

“…<p dir="ltr"><b>Abstract:</b><br>We propose a scalable, low-cost intervention to reduce urban heat on major roads and highways by applying a controlled micro-sprinkling of water during late-evening hours, when solar radiation is low and vehicle traffic has decreased. …”