Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”

Data Sheet 4_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf by Erman Wu (19021269)

“…</p>Methods<p>Using Global Burden of Disease 2021 data from 204 countries (1990-2021), we analyzed age-standardized mortality rates (ASMR) and disability-adjusted life years (DALY) for PMP-attributable LRIs, stratified by Socio-demographic Index (SDI), pollution source, and demographics. …”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”

Statistical data. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Sensitivity of land types to threat factors. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…In order to compare N/P efficiency more intuitively, we combined N/P content, N/P uptake, N/P uptake efficiency and N/P recover efficiency to calculate N/P comprehensive efficiency.…”

Data Sheet 1_Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study.pdf by Yan Xia (534241)

“…</p>Conclusions<p>Compared with IMRT, TOMO decreases the incidence of radiation pneumonitis but fails to improve acute skin toxicity. …”

Table 1_Global, regional, and national burdens of rheumatoid arthritis among people aged 60 years and older from 1990 to 2021: a trend analysis for the Global Burden of Disease Stu... by Qin-Yi Su (14188151)

“…Background<p>Rheumatoid arthritis (RA) poses a significant global health burden, especially among individuals aged 60 and older. …”

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... by Neves P.D.M.M. (20408168)

“…The kidney is a frequent target of SARS-CoV-2, potentially developing lesions in glomeruli, vessels, and tubulointerstitium in response to this infection. Herein we present the analysis of the first large Latin American cohort of adult patients undergoing kidney biopsy due to COVID-19-associated kidney disorders. …”

Table 1_Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort.docx by Mary Ngongang Kameni (20924126)

“…Our most significant findings include the association of double mutant alleles (AA) of rs4646140 and rs2074192 in the ace2 gene with decreased IL-6 and IL-2 expression levels respectively in TB-COVID-19 participants. …”

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx by Mehri Hajiaghayi (19822665)

“…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…</p><p><br></p><p dir="ltr">This study investigated the role of AR in chemotherapy response using two AR-positive breast cancer cell lines. We assessed responses to multiple chemotherapeutic agents—palbociclib, docetaxel, doxorubicin, paclitaxel, and cisplatin. …”

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity by Mengyu Liu (2890397)

“…<p>Trimethyltin chloride (TMT) is widely used as a constituent of fungicides and plastic stabilizers in the industrial and agricultural fields, and is generally acknowledged to have potent neurotoxicity, especially in the hippocampus; however, the mechanism of induction of neurotoxicity by TMT remains elusive. Herein, we exposed Neuro-2a cells to different concentrations of TMT (2, 4, and 8 μM) for 24 h. …”

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. by DIMITRIOS KIMOGLOU (20499350)

“…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …”

Effort variation with <i>η</i>. by Ankur Kamboj (19846178)

“…<p>Distribution of driving and exploratory effort (averaged across 128 Monte Carlo runs) with means and 95% confidence bounds across trials as <i>η</i> is varied around its fitted value 3.1742. …”

Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer by Robert J. Lake (22408833)

“…<b>B,</b> Auranofin response in SKOV3 cells stably expressing <i>NOTCH3</i> shRNA. Data are means ± SEM (<i>n</i> = 2 biological replicates). …”

Data Sheet 1_The dynamics of lowland river sections of Danube and Tisza in the Carpathian basin.pdf by Imre M. Jánosi (7480598)

“…Further significance tests are in progress, along with attempts at explanations. …”

Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes. by Zichao Liu (4591993)

“…(f) The harmonic means of intramembrane potassium and chloride concentrations increase, whereas for sodium, it decreases during neural activity. …”

Table_1_Toward workforce integration: enhancements in adaptive behaviors and social communication skills among autistic young adults following vocational training course.DOCX by Yael Lousky (20414456)

“…No significant Time x Group interaction was found for any of the examined measures, meaning similar trends were observed in all three vocational groups.…”

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx by Monika Marko (7926311)

“…Education resulted in equalizing the level of correctness of inhalation, which was similarly high for each type of device. This means that after education, all inhalers have similar difficulty levels in performing the correct inhalation technique. …”