Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx by Demos Kynigopoulos (12420457)

“…Increasing evidence implicates systemic metabolic dysregulation in AD pathogenesis, yet it remains unclear whether modulation of peripheral lipid and glucose metabolism can alter disease progression.</p>Methods<p>We investigated the effects of two FDA-approved metabolic agents—Alirocumab, a PCSK9 inhibitor that lowers LDL cholesterol, and Gliclazide, a sulfonylurea that enhances insulin secretion—in male 5xFAD mice, a transgenic model of AD. …”

Data Sheet 1_α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach.docx by Aimin Cai (6190532)

“…</p>Methods<p>In this study, we employed a nuclear magnetic resonance-based metabolomic approach to investigate the therapeutic effects of α-MT in a db/db mouse model of DN and explore the underlying molecular mechanisms.…”

Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx by Demos Kynigopoulos (12420457)

“…Increasing evidence implicates systemic metabolic dysregulation in AD pathogenesis, yet it remains unclear whether modulation of peripheral lipid and glucose metabolism can alter disease progression.</p>Methods<p>We investigated the effects of two FDA-approved metabolic agents—Alirocumab, a PCSK9 inhibitor that lowers LDL cholesterol, and Gliclazide, a sulfonylurea that enhances insulin secretion—in male 5xFAD mice, a transgenic model of AD. …”

Inhibition of p12 cleavage abolishes p8-induced conduit formation and cell aggregation. by Florian Simon (5387228)

Inhibition of p12 cleavage does not affect HTLV-1 cell-to-cell transmission from C91-PL to Jurkat. by Florian Simon (5387228)

Table 2_Integrated effects of Kampo treatment on gastrointestinal symptoms and stress in patients with functional dyspepsia: a preliminary prospective observational study.docx by Lian Liang (11550511)

“…Additionally, there was a significant decrease in negative mood components (anger and depression) and total mood disturbance. …”

Table 1_Integrated effects of Kampo treatment on gastrointestinal symptoms and stress in patients with functional dyspepsia: a preliminary prospective observational study.xlsx by Lian Liang (11550511)

“…Additionally, there was a significant decrease in negative mood components (anger and depression) and total mood disturbance. …”

Inhibition of p12 cleavage impairs HTLV-1 cell-to-cell transmission of chronically infected MT-2, but not C91-PL cells. by Florian Simon (5387228)

Table 1_Global burden of lower respiratory infections attributable to cytomegalovirus, 1990–2021: a systematic analysis from the MICROBE database.docx by Wanwan Zhang (1550911)

“…From 1990 to 2021, both ASMR and ASDR for CMV-attributable LRI decreased as SDI increased, and projections indicate a continued decline over the next 30 years.…”

Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Discussion<p>The capacity for infectious disease prevention and control among Guangxis grassroots hospital physicians has significantly improved following COVID-19. The high engagement in related training and emergency response efforts reflects a strong sense of professional identity and commitment. …”

Data Sheet 1_Spatiotemporal dynamics and influencing factors of native and invasive saltmarshes in a rapidly silting bay during 1985–2023.docx by Mingshan Xu (15370147)

“…Results showed that native saltmarshes significantly decreased from 632.24 ha to complete disappearance, while S. alterniflora expanded from zero to 2872.90 ha in Yueqing Bay during 1985-2023. …”

Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Discussion<p>The capacity for infectious disease prevention and control among Guangxis grassroots hospital physicians has significantly improved following COVID-19. The high engagement in related training and emergency response efforts reflects a strong sense of professional identity and commitment. …”

Elephant ethogram grouped by behavioral category. by Ana Belén López Pérez (22693281)

“…During the limited contact period, aggressive interactions were positively associated with fGCM concentrations, whereas a longer duration since first introduction was associated with a decrease. …”

Behavioral data collection summary. by Ana Belén López Pérez (22693281)

“…During the limited contact period, aggressive interactions were positively associated with fGCM concentrations, whereas a longer duration since first introduction was associated with a decrease. …”

Male elephant subjects included in the study. by Ana Belén López Pérez (22693281)

“…During the limited contact period, aggressive interactions were positively associated with fGCM concentrations, whereas a longer duration since first introduction was associated with a decrease. …”

ECC map. by Ana Belén López Pérez (22693281)

“…During the limited contact period, aggressive interactions were positively associated with fGCM concentrations, whereas a longer duration since first introduction was associated with a decrease. …”

Data set. by Ana Belén López Pérez (22693281)

“…During the limited contact period, aggressive interactions were positively associated with fGCM concentrations, whereas a longer duration since first introduction was associated with a decrease. …”

Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Supplementary file 1_Global, regional, and national burdens of MDR-TB attributable to smoking from 1990 to 2021 with a prediction from 2022 to 2050.docx by Du Dan (22274296)

“…Predictive analysis suggests that by 2050, deaths and DALYs of smoking-related MDR-TB, as well as their corresponding ASR, will continue to decrease.</p>Conclusion<p>The burden of MDR-TB worldwide, adjusted for age, and related to smoking, has shown a decline from 1990 to 2021. …”

Data Sheet 2_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.docx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”