The enriched GO terms of the 19 DECAGs. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Primers of the tested genes. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Summary of patient demographic characteristics. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Supplementary file 1_Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study.docx by Zhiyu Qiao (12514712)

“…For every 10 mL/min/1.73 m² increase in eGFR_diff, the incidence of various diseases decreased by approximately 10–19%.</p>Conclusion<p>eGFR_diff is significantly associated with increased risks of mortality, CVD incidence, and multiple CVD-related conditions. …”

Data_Sheet_1_Evaluating a computer-based body exposure paradigm for the treatment of body image disturbance in adolescent Anorexia Nervosa: effects on the attentional bias and emot... by Lena Sasse (20434616)

“…</p>Conclusions<p>While the existence of an AB was demonstrated, the carried-out body exposures were neither sufficient to reduce the AB nor the psychopathology; nevertheless, a significant decrease in anxiety levels showed the usefulness of the exposure sessions. …”

Table 1_Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large... by Changlan Li (704841)

“…A positive linear correlation was identified between ONSD values and discharge outcomes. …”

Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s... by Gonca Köse (21477470)

“…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …”

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX by Mingming Zhao (760369)

“…Nineteen identified metabolites, including five organic acids, four short-chain fatty acids, four amino acids, three fatty acids, and three benzenoids, differed significantly among the three groups, showing a strong association with VPA-induced hepatotoxicity. …”

Data Sheet 1_Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.docx by Pei Sun (115160)

“…</p>Setting<p>A tertiary university hospital in Beijing, China.…”

Data Sheet 2_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.pdf by figshare admin frontiersin (4545187)

“…</p>Objective<p>To evaluate feasibility and toxicity of plasma-cell targeting treatment using the subcutaneous anti-CD38 antibody daratumumab (Darzalex^®) in moderate to severe ME/CFS, and to assess the clinical course through 12–24 months follow-up after daratumumab intervention.</p>Methods<p>We performed a prospective, open-label pilot trial (EudraCT 2022–000281-18). …”

Data Sheet 1_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.pdf by Øystein Fluge (200378)

“…</p>Objective<p>To evaluate feasibility and toxicity of plasma-cell targeting treatment using the subcutaneous anti-CD38 antibody daratumumab (Darzalex^®) in moderate to severe ME/CFS, and to assess the clinical course through 12–24 months follow-up after daratumumab intervention.</p>Methods<p>We performed a prospective, open-label pilot trial (EudraCT 2022–000281-18). …”

Table_1_Outcomes of retroperitoneal fibrosis-related hydronephrosis and its risk factors for poor prognosis: a multi-center retrospective cohort study in Chinese patients.DOCX by figshare admin frontiersin (4545187)

“…Hydronephrosis is a common complication of RPF, however, its clinical features and outcomes have not been well elucidated.…”

European study sites. by Graeme T. Swindles (7192745)

“…We find that summer temperature is a significant climatic control on aPAR across our European sites. …”

Location of study sites. by Graeme T. Swindles (7192745)

“…We find that summer temperature is a significant climatic control on aPAR across our European sites. …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”

Changes of wind direction, wind speed and specific <i>orf2</i> amplicons during typhoon events for a range of years (2019–2020, n by Kuang-Yueh Chen (21071954)

“…Shades of blue, from dark (6-8 m/sec, largest) to light (0-2 m/sec, smallest), divided into 4 intervals, represent decreasing average wind speeds per hour (A). Comparison of aerosol concentrations (median values) between the north and south sides of the hills is illustrated (B, left), and the comparison of average northwesterly wind speeds per hours (median values) between the same regions, during typhoon landing, is illustrated (B, right). …”

Data Sheet 3_Esophageal cancer mortality trends in the United States: a comprehensive longitudinal study (1999–2023) using CDC WONDER data.xlsx by Xuefei Yang (2300221)

“…A significant decline in the mortality rate was observed over this period, with the overall AAMR decreasing from 6.74 to 5.61 per 100,000, corresponding to an AAPC of −0.81* (*p-value < 0.05). …”

Data Sheet 1_Esophageal cancer mortality trends in the United States: a comprehensive longitudinal study (1999–2023) using CDC WONDER data.xlsx by Xuefei Yang (2300221)

“…A significant decline in the mortality rate was observed over this period, with the overall AAMR decreasing from 6.74 to 5.61 per 100,000, corresponding to an AAPC of −0.81* (*p-value < 0.05). …”

Data Sheet 2_Esophageal cancer mortality trends in the United States: a comprehensive longitudinal study (1999–2023) using CDC WONDER data.xlsx by Xuefei Yang (2300221)

“…A significant decline in the mortality rate was observed over this period, with the overall AAMR decreasing from 6.74 to 5.61 per 100,000, corresponding to an AAPC of −0.81* (*p-value < 0.05). …”

Table1_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review and... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”