Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. حسب Richard Junior Zapata Dongo (17912565)

Anecdotal case of regression in a clam with naturally acquired BTN. حسب Rachael M. Giersch (22331947)

Negative (Prednisone) and basal (ATP) control compounds binding to ALK protein. حسب Richard Junior Zapata Dongo (17912565)

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

"…As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. Dominated by the mixed region, the total energy variation of the electrode decreases as the interlayer spacing decreases, with energy changes of 8526.52, 7443.52, and 6640.99 kJ·mol^–1 at interlayer spacings of 1.2, 1.0, and 0.8 nm, respectively, representing reductions of approximately 12.7 and 22.1% compared to 1.2 nm. …"

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

"…As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. Dominated by the mixed region, the total energy variation of the electrode decreases as the interlayer spacing decreases, with energy changes of 8526.52, 7443.52, and 6640.99 kJ·mol^–1 at interlayer spacings of 1.2, 1.0, and 0.8 nm, respectively, representing reductions of approximately 12.7 and 22.1% compared to 1.2 nm. …"

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation حسب Kaiqing Sun (18715965)

"…As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. Dominated by the mixed region, the total energy variation of the electrode decreases as the interlayer spacing decreases, with energy changes of 8526.52, 7443.52, and 6640.99 kJ·mol^–1 at interlayer spacings of 1.2, 1.0, and 0.8 nm, respectively, representing reductions of approximately 12.7 and 22.1% compared to 1.2 nm. …"

S1 Data - حسب Richard Junior Zapata Dongo (17912565)

"…This interaction was further supported by a significant decrease of ALK phosphorylation in single and combination treatment with 300nM ABT-199. …"

RNA targets of Mod identified by RiP-Seq. حسب Amalia S. Parra (4173004)

"…Mod is expressed in larval brains and its loss leads to a significant decrease in the number of central brain NBs. …"

Apoptosis inhibitor abolished and restored rTsSPc-disrupted Caco-2 monolayer barrier integrity. حسب Qi Qi Lu (17721401)

ALKG1202R –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

ALKC1156Y –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

ALKL1196M –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

ALK^wt–ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. حسب Richard Junior Zapata Dongo (17912565)

Changepoint analysis in comparison of MarBTN-specific eDNA and cancer in hemolymph. حسب Rachael M. Giersch (22331947)

PGAM5 knockdown prevented rTsSPc from disrupting Caco-2 monolayer integrity. حسب Qi Qi Lu (17721401)

Multiple distinct outcomes observed in soft-shell clams (<i>Mya arenaria</i>) after natural infection with MarBTN. حسب Rachael M. Giersch (22331947)

Assessing Bivalves as Biomonitors of Per- and Polyfluoroalkyl Substances in Coastal Environments حسب Shannon E. Jones (17558652)

"…Despite the ecological and economic significance of coastal environments, monitoring efforts to identify PFAS in these regions are limited. …"