Data Sheet 1_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.docx by Heinz Wiendl (237353)

“…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …”

Data Sheet 2_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.csv by Heinz Wiendl (237353)

“…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …”

Table 1_Gut microbiota dysbiosis in people living with HIV who have cancer: novel insights and diagnostic potential.xlsx by Zhiman Xie (11446130)

“…The significantly decreased abundance of Bacteroides and Bacteroides vulgatus in PLWH-C showed a negative correlation with the Pathways in cancer pathway, and a positive correlation with Choline metabolism in cancer, Central carbon metabolism in cancer, and Proteoglycans in cancer pathways. …”

Data Sheet 1_CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer.zip by Wenjing Wang (181404)

“…Patients were grouped based on treatment efficacy to compare platelet subpopulation differences.</p>Results<p>We observed that CD107a+ and CD62P+ platelet subpopulations were reduced in liver cancer patients. …”

Clozapine for persons with neurodevelopmental disorders: a systematic review and expert recommendations for clinical practice by Hélène Verdoux (110251)

“…After clozapine initiation, a decreased frequency of challenging behavior persisting over time was reported in most participants included in clinical studies, and a significant reduction in the number of admissions in the population-based two-year mirror-image study. …”

Model diagnostics for old death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Model diagnostics for adult death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Model diagnostics for child death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Model diagnostics for all death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Model diagnostics for female death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Model diagnostics for male death events. by Xin Zhang (35492)

“…Results from the dual-pollutants model demonstrated that the effect of PM on the risk of RD mortality remained significant and slightly increased in magnitude. Moreover, composite pollutants exhibited a higher risk effect, reaching its peak after one week; however, there was a decrease in single-day cumulative effects as more pollutant types were included. …”

Supplementary Material for: Retrospective Analysis of Allergen Characteristics in Patients with Allergic Diseases in Sanmen, Zhejiang Province by figshare admin karger (2628495)

“…The serum total IgE positivity rate was highest in the ≤12 age group and declined with age, with a resurgence observed in individuals over 60. Similarly, the positivity rates for Dermatophagoides spp. allergens and cow's milk also decreased with age. …”

Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled... by Jilei Hu (10156880)

“…Furthermore, the score of AMS in the curcumin group were lower than those in the placebo group at T₃, although with no significant difference. Gut microbiota analysis indicated that curcumin significantly increased the abundance of butyrate-producing bacteria Roseburia, Lachnospira, and Sellimonas while decreasing the abundance of Alistipes and Escherichia at high-altitude environments. …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism.tif by Xiaoya Wang (297374)

“…The 16S rRNA results revealed that CMME significantly increased gut microbiota richness and diversity and reduced the abundance of Bacteroides compared with Mod group significantly. …”

Table 1_Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism.xlsx by Xiaoya Wang (297374)

“…The 16S rRNA results revealed that CMME significantly increased gut microbiota richness and diversity and reduced the abundance of Bacteroides compared with Mod group significantly. …”

Table 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.xlsx by Yanling Wen (552195)

“…Notably, the heightened suppressive function of HLA_DR⁺ Tregs in severe COVID-19 patients, with interactions between PF4 and CXCR3, contributed to the homeostasis of HLA_DR⁺ Tregs in severe COVID-19 patients. Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”

Supplementary file 4_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

“…Notably, the heightened suppressive function of HLA_DR⁺ Tregs in severe COVID-19 patients, with interactions between PF4 and CXCR3, contributed to the homeostasis of HLA_DR⁺ Tregs in severe COVID-19 patients. Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …”