<i>In vitro</i> and <i>in vivo</i> Bioactivity of Stomoxyn. by Erick O. Awuoche (4603582)

“…</b> Gene-silencing validation: The relative expression of <i>stomoxyn</i> was measured from dsGFP and dsStomoxyn<i>-</i>treated <i>Gff</i> flies, showing a significant decrease in expression (<i>p</i><0.0001) in the case of dsStomoxyn<i>-</i>treated group. …”

Table 1_Global, regional, and national burdens of rheumatoid arthritis among people aged 60 years and older from 1990 to 2021: a trend analysis for the Global Burden of Disease Stu... by Qin-Yi Su (14188151)

“…Background<p>Rheumatoid arthritis (RA) poses a significant global health burden, especially among individuals aged 60 and older. …”

Table 1_Dynamic decline in estimated glomerular filtration rate associated with in-hospital mortality risk in acute ischemic stroke patients after endovascular therapy: evidence fr... by Yanping Lin (3639220)

“…Baseline eGFR was not significantly associated with mortality (P = 0.223), whereas post-EVT eGFR demonstrated a pronounced time-dependent association. …”

Data Sheet 2_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... by Yao Wang (102387)

“…Older patients receiving SGLT2i had a greater incidence of euglycemic ketoacidosis (EKA) (OR 1.622, 95% CI 1.276-2.062, p = 0.000) and genitourinary infection (GUI) (OR 3.59, 95% CI 3.31-3.89, p = 0.00) than did those receiving GLP-1RA, and the opposite was true for acute kidney injury (AKI) (OR 0.902, 95% CI 0.854 - 0.952, p = 0.00). …”

Data Sheet 1_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... by Yao Wang (102387)

“…Older patients receiving SGLT2i had a greater incidence of euglycemic ketoacidosis (EKA) (OR 1.622, 95% CI 1.276-2.062, p = 0.000) and genitourinary infection (GUI) (OR 3.59, 95% CI 3.31-3.89, p = 0.00) than did those receiving GLP-1RA, and the opposite was true for acute kidney injury (AKI) (OR 0.902, 95% CI 0.854 - 0.952, p = 0.00). …”

FFD – main effect, original fibrosis burden. by Åshild Telle (22794721)

Image 2_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…Red meat’s impact was greater in females, while inadequate plant consumption affected males more significantly. …”

Image 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…Red meat’s impact was greater in females, while inadequate plant consumption affected males more significantly. …”

Image 3_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…Red meat’s impact was greater in females, while inadequate plant consumption affected males more significantly. …”

Table 1_Biomechanical mechanisms of multidirectional dynamic compensatory muscle fatigue induced by abnormal cervical curvature: a cross-sectional case-control study based on surfa... by Rui Yang (293531)

“…During dynamic activities, muscle fatigue was exacerbated in the abnormal curvature group: during extension, the left UT showed significantly decreased MPF (p < 0.01) and MF (p < 0.05); during flexion, the left SCM exhibited significantly increased MPFs (p < 0.05) and MFs (p < 0.01). …”

Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analy... by L. Telisinghe (18706323)

“…</p><p dir="ltr">In this study, community-wide UTT and TB screening resulted in substantially lower TB incidence among PLHIV at population-level, compared to standard-of-care, with statistical significance reached in the final study year. There was also some evidence this translated to a decrease in self-reported TB incidence overall in the population. …”

Image 1_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif by Yi Kuang (1873354)

“…Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”

Image 2_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif by Yi Kuang (1873354)

“…Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”

Data Sheet 1_Global, regional, and national trends in ischaemic stroke burden and risk factors among adults aged 20 + years (1990–2021): a systematic analysis of data from the Glob... by Sibo Liu (9975065)

“…Males consistently faced a greater burden of IS across all subgroups. High systolic blood pressure and high low-density lipoprotein cholesterol (LDL-C) levels consistently represented the most significant risk factors contributing to DALYs from 1990 to 2021.…”

Supplementary Material for: Deficiency of p27kip1, a cyclin-dependent kinase inhibitor, accelerates topical elastase/3-aminopropionitrile fumarate salt-induced abdominal aortic ane... by figshare admin karger (2628495)

“…Conclusion: Knockout of p27 accelerated aneurysm growth with increased macrophage infiltration, VSMC loss, and decreased antioxidant factors, highlighting a potential role for p27 in AAA progression.…”

Operation framework of the SLSM mode. by Yichen Yin (6649409)

“…The application of the SLSM mode to a private machinery manufacturing company in Wenzhou resulted in the effective shouldering of safety responsibilities by the company, a year-on-year decrease in accident rates, and a significant increase in production efficiency, thereby providing corporate managers with guidance and suggestions for making improvements.…”

SLSM fishbone diagram. by Yichen Yin (6649409)

“…The application of the SLSM mode to a private machinery manufacturing company in Wenzhou resulted in the effective shouldering of safety responsibilities by the company, a year-on-year decrease in accident rates, and a significant increase in production efficiency, thereby providing corporate managers with guidance and suggestions for making improvements.…”

Image 1_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”