Image 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Image 4_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Table 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Image 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …"

Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel حسب Paras Wanjari (22259362)

"…The compounds demonstrated significant proton transport when combined with valinomycin, indicating transmembrane proton transport for <b>1a</b>–<b>c</b>. …"

Presentation 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

"…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"

Presentation 3_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

"…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"

Data Sheet 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... حسب Gyeong Ho Baek (21382907)

"…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"

Data Sheet 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... حسب Gyeong Ho Baek (21382907)

"…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"

Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

"…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"

Analysis of the circadian waveform of wild-type Drosophila at different temperatures using previously reported experimental data [59]. حسب Shingo Gibo (21762920)

Cilia disassembly proceeds at a faster rate in CCDC66-depleted cells, which is regulated by the AurkA-HDAC6 axis and rescued by microtubule stabilization. حسب Jovana Deretic (13113617)

"…Cilia length was quantified in 3D according to ARL13b signal (co-localizing with acetylated-tubulin). The mean cilia length in CCDC66-depleted cells decreased to 0.74-fold compared to the mean control length at 0 h. …"

Polysaccharides from Black Mulberry Attenuate Colitis through Gut Microbiota Mediated TNF-α/pNF-κB/ICAM‑1 Signaling Pathway حسب Li-Tao Yi (13780216)

"…These findings suggest PBM as a natural therapeutic agent for colitis, offering a multifaceted approach to restoring gut homeostasis through microbiota modulation and inflammatory pathway regulation. …"

Raw data. حسب Guohui Zhao (4668682)

"…The recorded stroke speeds were 108.87±13.57 km/h, 111.83±16.34 km/h, and 107.76±12.53 km/h for the low, medium, and high tension, respectively. A significantly higher ball speed was observed at 54lbs compared to both 48lbs and 60lbs (P <0.05). …"

The participants information. حسب Guohui Zhao (4668682)

"…The recorded stroke speeds were 108.87±13.57 km/h, 111.83±16.34 km/h, and 107.76±12.53 km/h for the low, medium, and high tension, respectively. A significantly higher ball speed was observed at 54lbs compared to both 48lbs and 60lbs (P <0.05). …"

Data Sheet 1_A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia.docx حسب Stephen B. Simons (19931955)

"…In sleep onset insomnia these changes in activity are weaker and may prolong the transition to sleep.</p>Methods<p>Using a wearable device, we compared 30min of short duration repetitive transcranial electric stimulation (SDR-tES) at 0.75Hz, prior to going to bed, with an active control at 25Hz in the same individuals.…"

Presentation 1_Sulforaphane as a promising anti-caries agents: inhibitory effects on Streptococcus mutans and caries control in a rat model.pdf حسب Meijiao Yu (20497592)

"…The growth of S. mutans and the biofilm formation were inhibited by SFN in a dose-dependent manner through suppressing the synthesis of extracellular polysaccharide (EPS) and acid production, as well as decreasing the acid tolerance. …"

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx حسب Susan Carroll (17468)

"…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …"

Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx حسب Susan Carroll (17468)

"…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …"

Effect size distribution and intersections of transcript usage response upon stimulation with <i>M</i>. <i>leprae</i> sonicate by T1R-free (LEP) and T1R-destined (T1R) leprosy pati... حسب Wilian Correa-Macedo (11813183)

"…<p>(<b>A</b>) Strip plot presenting the distribution of the mean fitted proportion difference (PΔ) between stimulated and non-stimulated samples by group. …"