Chemogenetic inhibition of Calcrl⁺ neurons attenuates chronic itch in multiple chronic itch models. by Huifeng Jiao (11537806)

“…<p><b>(A-C)</b> Allergic Contact Dermatitis (ACD) Model (n = 7 mice for each group): Experimental timeline showing intraspinal viral injection, ACD model induction, and behavioral testing phases <b>(A)</b>; Quantification of mechanical itch responses revealed significant CNO-mediated suppression in hM4Di mice, with no effect in vehicle-treated controls <b>(B)</b>; Spontaneous scratching frequency decreased following CNO administration <b>(C)</b>. …”

Genetic alterations of CD70 in DLBCL. by Kang Liu (423471)

“…Compared with DLBCL patients with CD70 mutation, methylation levels of PKHD1, MAS1, and FIP1L1 were obviously increased, whereas RPL10A, MARCH10, FAM45A, and FAM45B were significantly decreased in DLBCL patients with CD70 mutation. …”

Table 1_Impacts of surface wear of attachments on maxillary canine distalization with clear aligners: a three-dimensional finite element study.docx by Qiuying Li (565107)

“…Attachment wear led to a reduction in the efficiency of canine distalization. …”

Image 2_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 3_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 1_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 4_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Enhanced intrinsic excitability of spinal Calcrl⁺ neurons in chronic itch. by Huifeng Jiao (11537806)

“…Unchanged maximal rise slope <b>(G)</b>; Reduced half-width <b>(H)</b>; Decreased AHP amplitude <b>(I)</b>; Increased number of spikes upon 100 pA depolarization <b>(J)</b>. …”

Hair-follicle-associated pluripotent (HAP) stem-cell-sheet implantation accelerates cutaneous wound closure and suppresses scar formation in a mouse model by Koya Obara (12009506)

“…Expression levels of TGF-β1, COL1A2 and COL3A1 mRNA in the wound were significantly decreased in HAP stem cell-implanted mice compared with non-implanted control mice. …”

Table 1_Dupilumab relieves pruritus both in uremic pruritus and in atopic dermatitis with chronic kidney disease: a retrospective real-world study.docx by Qian Wang (32718)

“…</p>Results<p>After dupilumab treatment, the PP-NRS and 5D-IS scores of 12 AD patients with CKD and 10 UP patients were significantly decreased. The percentages of UP patients who achieved PP-NRS ≥ 4-point improvement and 5D-IS ≤ 10-point at week 4, 12, and 16 did not significantly differ from those of AD patients with CKD (p > 0.05). …”

Video 2_Contrast-enhanced ultrasound diagnosis and efficacy prediction of primary breast lymphoma: a case report and literature review.mp4 by Siqi Tang (3998222)

“…After more than two years of chemotherapy, CEUS revealed significant lesion shrinkage with well-defined margins alongside delayed arrival time, reduced peak intensity, and a decreased area under the curve, collectively indicating a favorable chemotherapeutic response. …”

Video 1_Contrast-enhanced ultrasound diagnosis and efficacy prediction of primary breast lymphoma: a case report and literature review.mp4 by Siqi Tang (3998222)

“…After more than two years of chemotherapy, CEUS revealed significant lesion shrinkage with well-defined margins alongside delayed arrival time, reduced peak intensity, and a decreased area under the curve, collectively indicating a favorable chemotherapeutic response. …”

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> by Ge Qiao (21802511)

“…A Cox proportional hazards model was employed to evaluate the prognostic significance and survival impact of these genes. …”

GO and KEGG pathway analyses of the DE-mRNAs. by Meimei Xu (744867)

“…The color transition from blue to red indicates decreasing <i>P</i> values, indicating increasingly significant differences. …”

Table 1_Efficacy and safety of esketamine in patients undergoing painless gastrointestinal endoscopy: a systematic review and meta-analysis of randomized controlled trials.doc by Qi Zhang (28502)

Effects of Alteration in ATF3 expression on neurological function and local brain edema in mice with ICH. by Tao Cui (124471)

“…Compared with the ICH model group, the water content in the basal ganglia of mice with ATF3 overexpression was significantly increased, while that in the ATF3 downregulation group was significantly decreased. …”

Table 1_A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021).docx by José-Manuel Ramos-Rincón (10428656)

“…IHM rose with age, from 0.8% in patients aged 18–39 to 31.7% in those ≥80 years (p < 0.001), but significant decreases were observed across all age groups after vaccination, especially in those ≥80 years (AOR: 0.76, 95% CI: 0.75–0.79, p < 0.001). …”

Table 1_Socio-hydrology and sustainable tank management: empirical case from a Mailam tank cascade, Tamil Nadu, India.xlsx by Raj Rengalakshmi (12058247)

“…The dependence on tanks for irrigation by farmers in the study area has decreased, ranging from 9 to 54%. There has been a significant change in land use; a 44% reduction in the area under cropping (1,707 ha to 954 ha), with a 13% increase in fallow land (1,607 ha to 1,822 ha) and a 43% increase in other vegetation and built-up area from 5 ha to 60 ha. …”

Data Sheet 1_Impact of finerenone on chronic kidney disease progression in Chinese patients with type 2 diabetes: a FIGARO-DKD subgroup analysis.docx by Ping Li (31981)

“…Finerenone resulted in a numerical decrease in the risk of the cardiovascular composite outcome (hazard ratio 0.91; 95% confidence interval 0.50–1.67) and a significantly reduced risk of the key secondary kidney outcome (hazard ratio 0.48; 95% confidence interval 0.29–0.79; p = 0.0029). …”

Data Sheet 1_Effects of cattle manure and sludge vermicompost on nutrient dynamics and yield in strawberry cultivation with distinct continuous cropping histories in a greenhouse.d... by Xiaofeng Bai (711688)

“…In both substrate types, there was a substantial increase in microbial population and enzyme activity, accompanied by a significant decrease in phenolic acid content. …”