Data Sheet 2_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

“…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Image 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.tif by Haiyan Liao (6100043)

“…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Data Sheet 4_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

“…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Data Sheet 5_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

“…RNA pull-down, RNA immunoprecipitation (RIP), and actinomycin D experiments were used to show that circ_0074158 impacts endothelial barrier function in sepsis by reducing the stability of the host gene CTNNA1 (mRNA) after binding to EIF4A3.</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”

Data Sheet 1_The efficacy of ophiopogonanone B in treating the cough in mice infected with Mycoplasma pneumoniae.docx by Nan-Nan Liu (12093551)

“…Subsequent immunohistochemistry and RT-PCR revealed a significant reduction (P < 0.01 or P < 0.05) in the proteins and mRNA expression levels of TRPA1, SP, and CGRP in the lung tissue of mice treated with high and medium doses of ophiopogonanone B.…”

Data Sheet 1_Unlocking the adaptation mechanisms of the oleaginous microalga Scenedesmus sp. BHU1 under elevated salt stress: a physiochemical, lipidomics and transcriptomics appro... by Rahul Prasad Singh (20283954)

“…<p>Microalgae are vital for their photosynthetic abilities, contributing significantly to global oxygen production, serving as a key trophic level in aquatic ecosystems, aiding in biofuel production, assisting in wastewater treatment, and facilitating the synthesis of valuable biochemicals. …”

Mean blood glucose responses (mmol/L) to an oral blood glucose bolus 2g/kg during a 120-minute period and mean area under the curve (mmol/L.min) during the oral blood glucose toler... by Elsie D. Oduor (22521785)

Mean blood glucose responses (mmol/L) to an oral blood glucose bolus 2g/kg during a 120-minute period and mean area under the curve (mmol/L.min) during the oral blood glucose toler... by Elsie D. Oduor (22521785)

Trends of uptake of delivery by CS and trends of the uptake of maternity incentives among women who had at least a live birth and gave birth in HFs one year prior to the three most... by Resham B. Khatri (10949429)

Table 1_To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux.docx by Chenglin Jia (578595)

“…</p>Results<p>Ruanjian Qingmai granules significantly decreased lipid deposition and significantly increased the expression of CYP7A1 mRNA in both zebrafish and HepaRG cells. …”

Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip by Qiwei Zhao (12519351)

“…Moreover, CAP inhibited glutamate release while enhancing BECN1-SLC7A11 binding, suggesting a reduction in SLC7A11 activity through the AMPK/BECN1 pathway. …”

Variation of T₂ spectrum of 0.38 water–binder ratio of concrete during F–T process under standard curing conditions: (a) Air content = 1.5%; (b) Air content = 3.6%; (c)... by YongHe Liu (20477123)

Estimated marginal mean values representative of the average time on ball and the relative frequency of ball touches and releases per minute of match duration, performed by profess... by Emily Escreet (20552634)

Patient Example. by James M. Friedman (22522150)

Topology-Driven Mechanical Behavior of Liquid Crystal Elastomers via a Dynamic Mechanical Analyzer by Yan-Ting Lin (9345296)

“…Stress relaxation experiments revealed that the synthesized liquid crystal elastomers (LCEs) exhibited significant stress relaxation behavior at 80 °C. Furthermore, when the LCEs were heated to 80 °C without applied stress, their molecular alignment decreased. …”

Topology-Driven Mechanical Behavior of Liquid Crystal Elastomers via a Dynamic Mechanical Analyzer by Yan-Ting Lin (9345296)

“…Stress relaxation experiments revealed that the synthesized liquid crystal elastomers (LCEs) exhibited significant stress relaxation behavior at 80 °C. Furthermore, when the LCEs were heated to 80 °C without applied stress, their molecular alignment decreased. …”

The Human Disharmony Loop Clinical Presentation. by James M. Friedman (22522150)

Pain and Function Outcomes Following PM Tenotomy. by James M. Friedman (22522150)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…However, how global land use changes impact soil N supply and potential N loss remains elusive. By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

A. Western blot showing accumulation of FoxD3 in CR+DBZ-treated crypt extracts from the colons of Dclk1^ΔIEC mice. by Kafayat Yusuf (22104155)