Image 3_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg by Kaisong Huang (5412626)

“…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”

Image 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg by Kaisong Huang (5412626)

“…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”

<b>Data used for analyses in the manuscript 'Sleep Regularity and Duration are Associated with Depression Severity in a Nationally Representative United States Sample'</b> by Katherine Maki (7445153)

“…</p><p dir="ltr"><b>Results: </b>Among participants (n=7297), we found associations between sleep-associated variables and SRI, with increased daytime sleep being the strongest correlate of decreased SRI. …”

Table 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.docx by Weichao He (16832265)

“…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …”

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…Cellular experiments further investigated the expression of cholesterol metabolism-related proteins and the effect of the cholesterol-depleting agent Methyl-β-cyclodextrin (MβCD) on DLBCL cells.</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”

Data Sheet 1_Global, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.docx by Qiyun Cheng (22074758)

“…Utilizing data from the Global Burden of Disease (GBD) 2021, we have updated the epidemiological trends of pneumoconiosis.…”

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf by Juanjuan Zhang (432819)

“…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …”

Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf by Miguel Ângelo-Dias (20936444)

“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf by Miguel Ângelo-Dias (20936444)

“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx by Xinxin Li (281237)

“…Furthermore, we observed that enforced upregulation of SMAD4 resulted in enhanced cytotoxicity of NK cells towards CRC cells. …”

Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... by Huihui Zhu (4483621)

“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”

Table 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.xlsx by Ye Li (290115)

“…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …”

Image 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.tif by Weichao He (16832265)

“…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …”

Mass spectrometry of Pparα-En4 pulldown proteins. by Tingting Jiang (169999)

“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”

Table 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.docx by Kaisong Huang (5412626)

“…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”

Data Sheet 1_Soil fungal community and co-occurrence network patterns at different successional stages of black locust coppice stands.docx by Huimei Tian (499744)

“…Significant changes in the relative abundance of certain fungal guilds were observed by both stand conversion and seasonal variation (p < 0.05). …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”

<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b> by Nelly Mauras (8103110)

“…Associations with glycemic and cognitive measures were assessed.</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …”

Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip by Peixi Zhao (620068)

“…</p>Methods<p>Using data from the GBD 2021 data, we conducted a secondary analysis. We assessed the prevalence, mortality, and disability-adjusted life years (DALYs) of MS across 204 countries/territories from 1990 to 2021, calculating age-standardized rates.…”