Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Data Sheet 1_The effects of acupoint catgut embedding therapy on anthropometric parameters and endocrine function in obese women: a systematic review and meta-analysis.pdf by Shuangqiu Li (8083634)

“…Hormonal changes included decreased LH and FSH and increased E2.</p>Conclusion<p>Our meta-analysis demonstrates that ACET significantly improves anthropometric parameters and endocrine function in obese women, though it does not significantly impact lipid metabolism or insulin resistance. …”

Image 1_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.tif by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Table 2_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.doc by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Table 1_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.doc by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Image 2_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.tif by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…<p>Sleep disturbances are common in Alzheimer’s disease (AD) and AD-related dementia (ADRD). We performed a sleep study on Tg-SwDI mice, a cerebral amyloid angiopathy (CAA) model, and age-matched wild-type (WT) control mice. …”

Data_Sheet_1_Exercising educational equity using California’s physical fitness data: a call for more school physical fitness programs, data, and research.docx by Da’Shay Templeton (19802262)

“…The lack of safe and affordable options for physical activity coupled with the significant decrease in physical activity rates among most American children underscores the need for programs, data, and research on physical fitness in schools, where children spend a significant amount of their time. …”

The upper plots show the changes in ZMK for summer and autumn. by Peyman Karami (5909264)

“…<p>Red indicates an increasing trend and green indicates a decreasing trend in fire density. The lower plots show significant increasing and decreasing trends for different biomes in Iran.…”

Annual distribution of IG-ralated AE reports. by Shaozhi Liu (13720340)

“…In pregnant women, hypoglycaemia (IC025 = 4.25) was detected as a strong signal, hypoglycaemia neonatal (IC025 = 2.96) as a medium signal, while ketoacidosis (IC025 = 0.76), decreased insulin requirement (IC025 = 0.24), and underweight (IC025 = 0.09) were identified as weak signals. …”

Proportion of AEs by SOCs in pregnant women. by Shaozhi Liu (13720340)

“…In pregnant women, hypoglycaemia (IC025 = 4.25) was detected as a strong signal, hypoglycaemia neonatal (IC025 = 2.96) as a medium signal, while ketoacidosis (IC025 = 0.76), decreased insulin requirement (IC025 = 0.24), and underweight (IC025 = 0.09) were identified as weak signals. …”

Table 2_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 3_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Image 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.jpg by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Data Sheet 1_Impact of multiple environmental factors on influenza–like illness in Fujian Province, China, 2015–2023: a multicity study.zip by Xiaoyan Yao (8723622)

“…Introduction<p>Influenza-like illness (ILI) represents a significant global public health challenge influenced by environmental factors. …”

Data Sheet 1_The sigma factor σ54 (rpoN) functions as a global regulator of antibiotic resistance, motility, metabolism, and virulence in Clostridioides difficile.docx by Ying Yang (24175)

“…Additionally, rpoN deletion led to a decrease in glucose metabolic rate, which we attribute to the downregulation of glycolytic enzymes. …”

Potential of Fenfuro^®, a novel, standardized <i>Trigonella foenum-graecum</i> (Fenugreek) seed extract, in ameliorating glycation-mediated amyloidogenesis by Sreemoyee Saha (20391298)

“…It was determined that these significant spectral changes were due to a combined effect of the protein as well as non-protein part of the extract and not attributable to any single bioactive component. …”

Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…<p>In late 2019, the conditional approval process for drugs in China transitioned from a pilot project to a formal program. Our study comprehensively analyzed 103 conditional approvals (CAs) authorized by the National Medical Products Administration (NMPA) from 2020 to 2023, specifically focusing on their characteristics, clinical evidence, and implementation effects. …”