Showing 3,421 - 3,440 results of 18,438 for search 'significantly ((((((we decrease) OR (largest decrease))) OR (mean decrease))) OR (a decrease))', query time: 0.62s Refine Results
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    Quantitative Proteomics Unveils the Synergistic Effects of Combination Drugs on Cytoskeleton Composition and Autophagy-Mediated Cell Death in Neuroblastoma by Pei-Chen Yu (1860772)

    Published 2025
    “…The mRNA expression levels of several genes predicted by LINCS also decreased. To comprehensively understand the mechanism behind superior efficacy of the combination therapy compared to monotherapy, we performed quantitative proteomics with tandem mass tag labeling and identified 3416 proteins from 20,623 peptides. …”
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    The spheroid assay is used to assess long-term effects of therapy on tumor cell by culturing the tumor cells in a micro-mass, which is a 3D tumor mass used as a surrogate for in vi... by Bryan S. Margulies (21492667)

    Published 2025
    “…<p>(A) MCF7 tumor cell micro-mass cultures (purple staining) treated with 0-, 1-, 2-, 2.5-, 5-, and 10-mM N-allyl noroxymorphone doses, after 336-hours, produced a significant decrease of 41.9% and 68.1% in micro-mass areas for the 5- and 10-mM N-allyl noroxymorphone concentrations, respectively (* = p < 0.014 and **** = p < 0.0001). …”
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