Genetic evidence linking gastroesophageal reflux disease to chronic kidney disease and kidney failure: a two-step Mendelian randomization study by Fanghong Zheng (8931326)

“…Interventions with these factors could significantly decrease the burden of CKD attributable to GERD.…”

None - by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”

Image_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.JPEG by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Table_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.DOCX by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome by Geoffrey S. Kelly (21537766)

“…After adjustments, droperidol use was associated with a reduced length of stay (mean ratio 0.76; 95% CI: 0.62 0.94; <i>P</i> = 0.01), decreased total medication administration (OR 0.34; 95% CI: 0.20–0.58; <i>P <</i>0.001) and decreased usage of opioids (OR 0.16; 95% CI: 0.07–0.39; <i>P <</i>0.001). …”

Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf by figshare admin frontiersin (4545187)

“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”

Image 1_SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.tif by Junchen Pan (19417598)

“…RT-PCR and Western blot analyses were used to investigate the relevant molecular mechanisms.</p>Results<p>We show that SQLE is significantly overexpressed in pancreatic cancer, and abrogation of SQLE results in a significant increase in squalene accumulation within tumor cells. …”

Data Sheet 1_Shifts in soil microbial and nematode communities over progression of pine wilt disease occurring in Pinus koraiensis stands.pdf by Siyu Tian (9874001)

“…Consequently, we observed a lower inter-kingdom network complexity in the soil community of the pines following the PWD, in which the bacterial networks decreased but fungal networks increased in complexity. …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for α-diversity index were estimated using a random effects model. …”

Upper extremity orthopedic softball injuries presenting to the emergency department: epidemiology across the lifespan by David F. Painter (12884672)

“…The average incidence rate of UE injuries from 2012–2021 was 187.9 per 100,000 persons, with a significant decrease in injury incidence across the timespan (<i>p</i> < .001). …”

Data Sheet 1_An in vitro evaluation of intravenous lipid emulsion on three common canine toxicants.docx by Emery Jones (19736377)

“…ILE therapy may have other means of significantly decreasing lipophilic drug concentration in cases of toxicosis.…”

Accuracy rates for deductive (categorical and propositional) and inductive (propositional) arguments before and after left inferior frontal gyrus tDCS. by Shane Fresnoza (8409477)

“…Pairwise comparisons were Bonferroni corrected with a significance level of <i>p</i> ≤ 0.05. Data are presented as mean ± standard error of mean.…”

Accuracy rates for deductive and inductive arguments before and after tDCS of the left dorsolateral prefrontal cortex. by Shane Fresnoza (8409477)

“…Pairwise comparisons were Bonferroni corrected with a significance level of <i>p</i> ≤ 0.05. Data are presented as mean ± standard error of mean.…”

Data Sheet 1_Changes in the community composition and function of the rhizosphere microbiome in tobacco plants with Fusarium root rot.docx by Min Yang (146229)

“…In the root tissues of diseased plants, the Shannon index of bacterial and fungal communities decreased by 17.71–27.05% (P < 0.05). Additionally, we observed that the rhizosphere microbial community of diseased tobacco plants shifted toward a pathological combination, with a significant increase in the relative abundance of harmful microbes such as Alternaria, Fusarium, and Filobasidium (89.46–921.29%) and a notable decrease in the relative abundance of beneficial microbes such as Lysobacter, Streptomyces, Mortierella, and Penicillium (48.48–81.56%). …”

Table1_Evaluation of thyroid function tests among children with neurological disorders.docx by Haojie Meng (20400383)

“…Compared with controls, free thyroxine (FT4) levels were significantly decreased in neurological disorders in meta-analysis (MD = -0.29, 95% CI: -0.50 to -0.09), whereas thyroid-stimulating hormone (TSH) levels showed no significant difference (MD = -0.07, 95% CI: -0.36 to 0.21). …”

Table 1_Effects of different dosages/frequency of Xuebijing injection (a Chinese patent) for sepsis: a network meta-analysis of randomized controlled trials.docx by Guangyan Liu (716821)

“…</p>Methods<p>We examined eight databases for 1,765 randomized controlled trials published before July 2024, organized the literature using NoteExpress software and extracted data using Microsoft Excel software. …”

Image 3_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data Sheet 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.csv by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data from: '<b>From climate warming to accelerated cellular ageing: an experimental study in a wild passerine bird'</b> by Antoine Stier (3596369)

“…</i> higher thyroid hormones levels, increased expression of glucocorticoid receptor, increased mitochondrial density) leading to a reduction in telomere maintenance mechanisms (<i>i.e.</i> non-significant decrease in the gene expression of telomerase and protective shelterin). …”

Table 1_Targeting APE1/Ref-1 to alleviate formalin-induced pain and spinal neuro-inflammation in rats: a promising therapeutic approach.xlsx by Eman Elgendy (21811052)

“…We inhibited the redox function of APE1 using E3330 and assessed its effects on pain behavior. …”