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largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), gy decreased (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), gy decreased (Expand Search)
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4421
Image 2_Pan-cancer analysis of phagocytosis regulators in female-specific cancers: a focus on HMGB2.tif
Published 2025“…Furthermore, when HMGB2 knockdown was combined with Palbociclib treatment, a significant decrease in tumor cell proliferation was observed across multiple cancer models.…”
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4422
Image_3_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.tif
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”
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4423
Table 1_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”
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4424
Table_2_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”
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4425
Supplementary Material for: Alcohol use and types and ischemic stroke: a systematic review and meta-analysis
Published 2025“…Moderate alcohol use was associated with significant decrease in ischemic stroke risk (RR=0.87; 95% CI 0.83-0.92) while heavy alcohol use was associated with significant increase in ischemic stroke risk (RR=1.31; 95% CI 1.19-1.44). …”
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4426
Data Sheet 1_Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-anal...
Published 2025“…There was no statistically significant decrease in CD8<sup>+</sup> cells. For inflammation, lower-dose Tα1 could significantly reduce C-reactive protein (CRP) levels (mg/L) (MD=-30.12, 95%CI [-35.75, -24.49], P<0.00001), while higher-dose Tα1 showed no statistically significant difference (MD=-3.83, 95%CI [-12.14, 4.49], P=0.37). …”
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4427
Table 1_Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreatio...
Published 2025“…Blood and urine samples collected at baseline, before, and after DHR were analyzed for inflammation-related biomarkers. VAS scores significantly increased while muscle strength decreased from baseline measures after DHR regardless of group assignment (main effect of time p < 0.001). …”
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4428
Data Sheet 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.docx
Published 2025“…The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. Standardized mean differences (MD) and 95% confidence intervals (CIs) were calculated.…”
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4429
HCl-gas etching behavior of (001) β-Ga<sub>2</sub>O<sub>3</sub> under oxygen supply
Published 2025“…At 747°C, the planar etch rate (PER) exhibited a slight decrease with increasing <i>P</i><sup>0</sup>(O<sub>2</sub>). …”
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4430
Image 2_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif
Published 2025“…The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. Standardized mean differences (MD) and 95% confidence intervals (CIs) were calculated.…”
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4431
Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf
Published 2025“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …”
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4432
Table 1_Pre-COVID era pediatric disease incidence in Kazakhstan: regional panel data analysis of multiple disease groups (2010–2019).xlsx
Published 2025“…</p>Results<p>Respiratory diseases showed the highest mean incidence (57,329.86 per 100,000), with significant regional variation. …”
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4433
Image 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif
Published 2025“…The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. Standardized mean differences (MD) and 95% confidence intervals (CIs) were calculated.…”
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4434
Supplementary Material for: Treatment of plaque psoriasis with guselkumab reduces systemic inflammatory burden as measured by neutrophil/lymphocyte ratio, platelet/lymphocyte ratio...
Published 2025“…In VOYAGE I, NLR (p=0.011), PLR (p=0.015) and MLR (p=0.004) decreased significantly following 16 weeks of guselkumab treatment vs. placebo. …”
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4435
Table 2_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.xlsx
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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4436
Image 2_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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4437
Table 2_Magnesium application partially reversed the negative effects of mulching on rhizosphere nitrogen cycling in a Phyllostachys praecox forest.docx
Published 2025“…To address this, our study investigated rhizosphere nitrogen cycling in Lei-bamboo across a short-term degradation cycle. We found that mulching enhanced the abundance of 16S-rRNA and nitrogen-cycling functional genes. …”
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4438
Image 7_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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4439
Hypermutability of <i>Mycolicibacterium smegmatis</i> due to ribonucleotide reductase-mediated oxidative homeostasis and imbalanced dNTP pools
Published 2025“…The Msm-Y252A displayed a 1.9-fold decrease in dATP and increases in dGTP (1.6-fold), dTTP (9.0-fold), and dCTP (1.3-fold). …”
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4440
Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf
Published 2025“…MB was associated with a significant decrease in cytophilic subclasses IgG1 and IgG3 to S and S2, and IgA to RBD, S and S2 in CCP units IgA to RBD, S and S2 in CCP units, without a reduction in neutralization titer and with a modest increase in IgG2 to RBD and S.…”