Image 1_SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.tif by Junchen Pan (19417598)

“…RT-PCR and Western blot analyses were used to investigate the relevant molecular mechanisms.</p>Results<p>We show that SQLE is significantly overexpressed in pancreatic cancer, and abrogation of SQLE results in a significant increase in squalene accumulation within tumor cells. …”

Data Sheet 1_Shifts in soil microbial and nematode communities over progression of pine wilt disease occurring in Pinus koraiensis stands.pdf by Siyu Tian (9874001)

“…Consequently, we observed a lower inter-kingdom network complexity in the soil community of the pines following the PWD, in which the bacterial networks decreased but fungal networks increased in complexity. …”

General participant characteristics. by Josephine Grandt (21512356)

“…The hepatic transcriptome changed significantly during a standardized meal and these changes were blunted in patients with NAFLD and cirrhosis. …”

Presentation 1_Germination responses of native fire ephemerals of Patagonian grasslands to smoke water and karrikinolide.zip by Sofía Gonzalez (245015)

“…Seeds collected on different harvest dates were incubated in a germination chamber, and germination responses were analyzed using Generalized Linear Models and Kaplan-Meier survival curves. KAR₁ significantly enhanced and accelerated germination in both species, with the strongest effect at the highest concentration (1/100). …”

Scale and environmental data for the analysis of year class growth of coregonids from Lake Starnberg by Maxim Teichert (20796416)

“…During the observed period, phosphorus concentrations decreased, indicating reduced nutrient availability, whereas spring temperatures showed no significant long-term trend. …”

Does policy integration in renewable energy deployment enhance environmental sustainability in Africa? by Mary Donkor (20463828)

“…Using data from 41 SSA countries from 1998 to 2020, we employ the generalized linear model (GLM) and panel quantile regression to address methodological challenges. …”

E4 assessment of physiological measures (Kondaurova et al., 2024) by Maria V. Kondaurova (19751735)

“…Children self-reported a significant increase in LE over time. However, their physiological measures demonstrated a trend indicating a decrease in LE. …”

Data Sheet 1_Changes in the community composition and function of the rhizosphere microbiome in tobacco plants with Fusarium root rot.docx by Min Yang (146229)

“…In the root tissues of diseased plants, the Shannon index of bacterial and fungal communities decreased by 17.71–27.05% (P < 0.05). Additionally, we observed that the rhizosphere microbial community of diseased tobacco plants shifted toward a pathological combination, with a significant increase in the relative abundance of harmful microbes such as Alternaria, Fusarium, and Filobasidium (89.46–921.29%) and a notable decrease in the relative abundance of beneficial microbes such as Lysobacter, Streptomyces, Mortierella, and Penicillium (48.48–81.56%). …”

Table1_Evaluation of thyroid function tests among children with neurological disorders.docx by Haojie Meng (20400383)

“…Compared with controls, free thyroxine (FT4) levels were significantly decreased in neurological disorders in meta-analysis (MD = -0.29, 95% CI: -0.50 to -0.09), whereas thyroid-stimulating hormone (TSH) levels showed no significant difference (MD = -0.07, 95% CI: -0.36 to 0.21). …”

Table 1_Effects of different dosages/frequency of Xuebijing injection (a Chinese patent) for sepsis: a network meta-analysis of randomized controlled trials.docx by Guangyan Liu (716821)

“…</p>Methods<p>We examined eight databases for 1,765 randomized controlled trials published before July 2024, organized the literature using NoteExpress software and extracted data using Microsoft Excel software. …”

Image 3_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data Sheet 1_HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia.zip by Joanne K. Agus (12889409)

“…In exploring differences among HDL parameters from postprandial, overnight fasted, and 36-h fasted individuals, we observed that plasma HDL-cholesterol and apolipoprotein A-I concentrations remained unchanged. …”

Data Sheet 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.csv by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data from: '<b>From climate warming to accelerated cellular ageing: an experimental study in a wild passerine bird'</b> by Antoine Stier (3596369)

“…</i> higher thyroid hormones levels, increased expression of glucocorticoid receptor, increased mitochondrial density) leading to a reduction in telomere maintenance mechanisms (<i>i.e.</i> non-significant decrease in the gene expression of telomerase and protective shelterin). …”

Table 1_Targeting APE1/Ref-1 to alleviate formalin-induced pain and spinal neuro-inflammation in rats: a promising therapeutic approach.xlsx by Eman Elgendy (21811052)

“…We inhibited the redox function of APE1 using E3330 and assessed its effects on pain behavior. …”

DataSheet1_Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens.DOCX by Zhuoxuan Yu (20343486)

“…Membrane levels of Rab10 increased within day 1 of the cocaine treatment, subsequently decreasing at later time points. Rab10 deficiency in NAc regions significantly increased cocaine-inhibited membrane GABA_BR levels and inhibited cocaine-induced hyperlocomotion and behavioral sensitization. …”

Data Sheet 4_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx by Fangming Wang (2810719)

“…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …”

Model fit for childhood CHI subscales. by Amalie Hundahl (22593238)

“…With increasing CHI scores, we observed a decrease in well-being (p = 0.004), and health-related quality of life (p=<0.0001–0.007). …”

Image 1_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data Sheet 3_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx by Fangming Wang (2810719)

“…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …”