Table 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.docx by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx by Amy K. Stark (20470996)

“…</p>Methods<p>Based on the previously characterized proinflammatory roles of prostanoid signaling in DR, we assayed the distinct prostanoid signaling mechanisms regulating inner and outer blood-retina barrier function using in vitro methods involving monoculture of primary human cells.…”

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx by Shenghua Lu (20762612)

“…Regarding neurological function, the BCP combination group significantly increased the Glasgow Coma Scale score (MD = 1.86, 95% CI 1.17 to 2.56, p < 0.00001) and decreased the National Institutes of Health Stroke Scale score (MD = −2.17, 95% CI −3.35 to −0.99, p = 0.0003). …”

Table_1_Outcomes of retroperitoneal fibrosis-related hydronephrosis and its risk factors for poor prognosis: a multi-center retrospective cohort study in Chinese patients.DOCX by figshare admin frontiersin (4545187)

“…They were followed up until death or September 2021, whichever came first.</p>Results<p>The mean age at diagnosis was 58.83 ± 12.13 years, and 80 patients (69.57%) were men. …”

Image 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 6_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 4_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 5_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 3_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Image 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx by Yanni Lan (9092615)

“…</p>Methods<p>We utilized comprehensive data sources from the Global Health Data Exchange (GHDx). …”

Table 1_Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome.docx by Miaohong Wang (8975903)

“…Restricted cubic spline analysis confirmed that these relationships were linear. The impact of age was significant, with OBS benefits only observed in those aged 40 and older.…”

DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx by Teng Qi (278739)

“…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. High GLI1 expression indicated better survival outcomes and was correlated with the age and stage of BRCA patients. …”

Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Bl... by figshare admin karger (2628495)

“…Results: Both groups showed a significant decrease in the percentage of multiple-step responses (p=0.013) and a shorter total recovery time to recover balance (p=0.006). …”

Data Sheet 1_Impact of primary production and net ecosystem metabolism on carbon and nutrient cycling at the land-sea interface.docx by Louise C. V. Rewrie (21016172)

“…When turbidity decreased in late spring (May), we observed elevated GPP rates, and highest GPP rates in summer (June-August), with seasonal averages of 613 ± 89 mg C m^-2 d^-1 in 2020 and 558 ± 77 mg C m^-2 d^-1 in 2021. …”

Supplementary file 1_Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY2.docx by Zhiqi Yang (2692909)

“…In the presence of nifedipine, LEFTY2 did not further modify trypsin induced increase of [Ca²⁺]_i. LEFTY2 significantly decreased levels of L-type Ca²⁺ channel.…”

Image 3_No change in key HIV target cell markers following initiation of three progestin-based hormonal contraception methods: findings from the CHIME study.tiff by Marisa R. Young (7919255)

“…There were statistically significant but moderate absolute decreases in proportion of CD45+ and CD4+ T cells in CVL, and CD4+ T cells in blood, and increased proportion of CD69+ T cells in blood post-HC. …”

Table 2_No change in key HIV target cell markers following initiation of three progestin-based hormonal contraception methods: findings from the CHIME study.docx by Marisa R. Young (7919255)

“…There were statistically significant but moderate absolute decreases in proportion of CD45+ and CD4+ T cells in CVL, and CD4+ T cells in blood, and increased proportion of CD69+ T cells in blood post-HC. …”