Data Sheet 1_Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.docx by Hua Huang (190195)

“…A dextran sulfate sodium (DSS)-induced colitis mouse model was developed, demonstrating that the protein expression levels of GNG5 in the colonic tissue of model mice were significantly decreased compared to controls w)ile the expression levels of TIMP1 were increased (p < 0.01). …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…We demonstrated that stretching increases the core size and shell thickness and decreases the generation frequency. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…We demonstrated that stretching increases the core size and shell thickness and decreases the generation frequency. …”

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…Typhimurium, among which the <i>StiP</i> deletion strain (263<i>ΔStiP</i>) showed the greatest serum resistance reduction (2.49-fold). We further explored the role of <i>StiP</i> in host blood environment adaptation and found that 263<i>ΔStiP</i> displayed 3.12-fold reduced HeLa cell adhesion, 3.74-fold lower HeLa cell invasion, 1.92-fold decreased intra-macrophage survival, and 50% reduced serum resistance versus wild-type 263 (WT263), collectively indicating that <i>StiP</i> is critical for host blood environment adaptation in invasive <i>S</i>. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…We demonstrated that stretching increases the core size and shell thickness and decreases the generation frequency. …”

Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... by Shao-jun Xu (11633956)

“…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …”

Table 1_Sex-specific association between triglyceride-glucose index and all-cause mortality in patients with osteoporotic fractures: a retrospective cohort study.docx by Shao-han Guo (19690687)

“…However, in males, there was a non-linear correlation, where patients in the uppermost TyG-I tertile showed a substantially decreased mortality risk relative to those in the lowest tertile (HR: 0.53, 95% CI: 0.30–0.92, p = 0.02). …”

Supplementary file 1_Sex-specific association between triglyceride-glucose index and all-cause mortality in patients with osteoporotic fractures: a retrospective cohort study.xlsx by Shao-han Guo (19690687)

“…However, in males, there was a non-linear correlation, where patients in the uppermost TyG-I tertile showed a substantially decreased mortality risk relative to those in the lowest tertile (HR: 0.53, 95% CI: 0.30–0.92, p = 0.02). …”

Table 1_Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005–2020.docx by Chaoyue Mo (21684056)

“…In males, a similar non-linear trend was observed for TG, with levels peaking at 3.0 cups/day before decreasing.…”

Image 4_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Image 1_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Image 5_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Table 2_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Image 3_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Data Sheet 1_The CML experience to elucidate the role of innate T-cells as effectors in the control of residual cancer cells and as potential targets for cancer therapy.pdf by Amandine Decroos (20222913)

“…This was particularly the case when considering iNKT cells for which surface-expression level of PD-1 even decreased relative to healthy control subjects. Lastly, we found a negative correlation between the proportion of innate CD8 T-cells expressing PD-1 and those expressing perforin in non-relapsed patients at D0. …”

Image 2_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Table 1_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Table 1_Housed feeding improves rumen health by influencing the composition of the microbiota in Honghe cattle.docx by Runqi Fu (15267554)

“…For rumen microbiota, the HES group significantly decreased alpha diversity. The core rumen bacterial communities were Bacteroidata, Firmicutes and Proteobacteria. …”

Data Sheet 1_Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma.docx by Ângela Marques-Magalhães (20924831)

“…Finally, the combinatory potential of MLo-1508 and sunitinib were asses both in vitro and in vivo using the ACHN cell line. We found that MLo-1508 significantly decreased RCC cell viability while inducing apoptosis in a dose-dependent manner without cytotoxicity for non-malignant cells. …”

Data Sheet 3_Pandan–vanilla rotation mitigates Fusarium wilt disease in vanilla: insights from rhizosphere microbial community shifts.xlsx by Shan Hong (1938337)

“…Crop rotation significantly increased fungal diversity and richness. …”