IRE1 depletion induces cell cycle arrest independently of apoptosis. by Iratxe Zuazo-Gaztelu (21071939)

IRE1 silencing downregulates cell cycle genes and engages TP53 and specific CDK inhibitors. by Iratxe Zuazo-Gaztelu (21071939)

Identification and validation of <i>Ctsz</i> as the lead candidate gene underlying <i>Tip5.</i> by Rachel K. Meade (22216529)

The sequences of si-RNAs used in this study. by Changji Li (4806930)

“…Our study observed a significant increase in CRNN expression in cSCC samples compared to healthy skin. …”

Primary antibodies used for immunoblot analysis. by Iratxe Zuazo-Gaztelu (21071939)

“…Known cancer dependency on IRE1 entails its enzymatic activation of the transcription factor XBP1s and of regulated RNA decay. We discovered surprisingly that some cancer cell lines require IRE1 but not its enzymatic activity. …”

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> leaves on A) ATP, B) p-mTOR, C) beclin-1, and D) p-AMPK levels. by Fatma A. Moharram (9276104)

IRE1 silencing downregulates cell cycle genes and engages TP53 and specific CDK inhibitors. by Iratxe Zuazo-Gaztelu (21071939)

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> on A) GSH, B) SOD, C) TNF-α, D) IL-1β, E) p-NF-κB, and F) Caspase-3 levels. by Fatma A. Moharram (9276104)

Growth of certain cancer cell lines requires IRE1 but not its enzymatic activity. by Iratxe Zuazo-Gaztelu (21071939)

Fuchioka dataset 251021. by Yusuke Fuchioka (22806178)

“…Recent advances in 3D-MRI analysis have enabled quantitative cartilage thickness measurement. We hypothesized that OWHTO would result in measurable decreases in the PF joint cartilage thickness, predominantly medially and detectable using quantitative 3D-MRI. …”

NS co-suppresses Ox-LDL-induced apoptosis in RAW264.7 cells. by Yihua Wang (491766)

Study design. by Moazzam Tanveer (20775814)

“…<div><p>Background</p><p>Childhood obesity poses a significant public health challenge, yet effective school-based physical activity (PA) interventions remain scarce, especially in Pakistan. …”

NS delays the formation of atherosclerotic plaques in ApoE^-/- mouse models. by Yihua Wang (491766)

NS attenuates ox-LDL-induced foam cell formation. by Yihua Wang (491766)

NS affects the PI3K/AKT/mTOR pathway in RAW264.7 cells. by Yihua Wang (491766)

NS enhances autophagy inhibits atherosclerosis in RAW264.7 cells. by Yihua Wang (491766)

NS suppresses inflammation induced by Ox-LDL in RAW264.7 cells. by Yihua Wang (491766)

NS affects lipid transport in ApoE^-/-mouse models. by Yihua Wang (491766)

Quantitative Proteomics Unveils the Synergistic Effects of Combination Drugs on Cytoskeleton Composition and Autophagy-Mediated Cell Death in Neuroblastoma by Pei-Chen Yu (1860772)

“…Additionally, the research indicated that cell cycle arrest occurred under combination therapy. Furthermore, we confirmed that the extent of autophagy significantly increased after the combination treatment. …”

NS restores macrophage autophagy and alleviates the progression of atherosclerosis by inhibiting the PI3K/Akt/mTOR pathway. by Yihua Wang (491766)