CLIC1 upregulation accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells. by Jingtong Xiong (22272139)

“…<p>(a-c) The activities of SOD (a), CAT (b), and GSH-Px (c) were significantly reduced in OGD/R-treated HT22 cells compared to the control group, with the restoration of these antioxidant enzyme activities upon CLIC1 silencing. …”

Data Sheet 1_Frustration and its impact on search and rescue canines.pdf by Sally Dickinson (254872)

“…Our results revealed significant decreases in heart rate variability following frustration and increased latency in the search task, suggesting that frustration had a more pronounced impact on the dogs' physiological state and performance compared to exercise. …”

Table 2_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

Table 1_Can fostering posttraumatic growth prevent burnout and promote resilience in future nurses?.docx by Jae-Chang Sim (22335904)

“…Although the effect on burnout was not statistically significant, there was a trend for relatively decreased burnout in the treatment group.…”

Supplementary file 1_An improved analytical method for anti-uplift stability of narrow foundation pit based on energy method.docx by Shuping Ren (1786975)

“…When the width of the foundation pit decreases from 1.5 times to 0.4 times its own width, the anti-uplift stability coefficient increases from 1.97 to 3.18, representing an increase by a factor of 1.61. …”

Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”

Insight into Greenhouse Gas Emission Characteristics of Light-Duty Vehicles in China Driven by Technological Innovation by Xinping Yang (17371783)

“…As anticipated, with advancements in emission standards and powertrains, vehicular GHG emissions have significantly decreased. However, our findings also revealed surprising trends. …”

Fig 3 - by Laura Garcia-Toscano (20477540)

“…<p>Hsp90 mutation or inhibition decreases accumulation of phosphorylated TDP-43 <b>A.…”

Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights by Wang B. (4026758)

“…Conclusion The SO2 inhalation protocol effectively establishes a CB model in dogs. SCT effectively treats CB by reducing mucin levels and may lower MUC5AC expression by decreasing acetylcholine and CHRM3.…”

Data Sheet 1_Antibacterial effects of coniferyl alcohol-derived dehydrogenation polymer on chlamydial infection in vitro.pdf by Anna Pfundner (22409281)

“…Infection and adhesion assays demonstrated a significant reduction in infection levels, suggesting that DHP/Alg directly targets Chlamydia elementary bodies, thereby disrupting their ability to adhere and initiate infection. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…C57BL/6J mice treated with two cycles of cisplatin (3.5 mg/kg) showed a significant elevation in ABR thresholds, along with loss of outer hair cells and inner hair cells synapse. …”

Table 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc by Yaojin Sun (21692411)

“…Background<p>Hemophilia, a genetic disorder characterized by deficiencies in clotting factors VIII or IX, often results in joint and muscle bleeding, leading to hemophilic arthropathy and reduced quality of life. …”

Data Sheet 1_Algicidal activity of Streptomyces sp. LMJ-114 against Microcystis aeruginosa.pdf by Mijia Du (18080947)

“…The treatments of both culture broth supernatant and mycelia of strain LMJ-114 significantly affected the contents of retinoic acids (RAs) and microcystins (MCs), and 4 days later, RAs eliminated completely, and 7 days later, microcystin RR (MC-RR) decreased by 96.7 and 87.9%, respectively, and microcystin LR (MC-LR) contents decreased by 89.9 and 81.0%, respectively. …”

Table 1_Ultrasonographic examination of the patellar ligament after capsular and fascial imbrication for the treatment of cranial cruciate ligament rupture in dogs.docx by Mario Candela Andrade (20932802)

“…Thickening of the patellar ligament after capsular and fascial imbrication (CFI) is a frequently reported complication, but its clinical significance remains unclear.…”

Data Sheet 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc by Yaojin Sun (21692411)

“…Background<p>Hemophilia, a genetic disorder characterized by deficiencies in clotting factors VIII or IX, often results in joint and muscle bleeding, leading to hemophilic arthropathy and reduced quality of life. …”

Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx by Yanzheng Xie (22596953)

“…</p>Methods<p>By leveraging the unique long-range focusing capability, we establish a tapered-fiber-probe (TFP) strategy enabling non-contact and highprecision near-infrared (NIR) optical pacing in zebrafish embryos, where sustained micron-scale spatial precision (3 μm FWHM) was achieved at physiologically relevant working distances.…”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

<b>Sampling strategies and mitigation of natural and anthropogenic effects in detrital zircon provenance analysis of fluvial strata</b> by Ting Bai (20472050)

“…The results from our study show that (1) the inflow of lower-order streams has a meaningful impact on the provenance signal of higher-order channels, but the impact distances are quite limited. (2) Lakes have significant hydraulic sorting effects on different-sized particles, and thus, complicate provenance signals, but trapping of zircon by lakes might be more limited. (3) The construction of dams would have a limited long-term impact on the detrital zircon provenance of rivers downstream if sediment could be discharged from the sediment pathway through the dam. (4) Anthropogenic erosion creates provenance signal enrichments of more easily eroded strata and can interfere with natural sediment sourcing. …”

Table 1_Projecting global shifts in the invasive potential of Bidens pilosa L. under climate change using species distribution models.xlsx by Linran Fan (2210911)

“…Our findings suggest a likely decline of suitable habitats in tropical regions and an expansion into temperate regions, with climate suitability decreasing under higher temperatures. …”

Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

“…Furthermore, both QWBZP decoction and QWBZP-TG decreased the levels of DAO, D-Lactate, sIgA, IL-6, and TNF-α in the AAD mice. …”