Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…<p>In late 2019, the conditional approval process for drugs in China transitioned from a pilot project to a formal program. Our study comprehensively analyzed 103 conditional approvals (CAs) authorized by the National Medical Products Administration (NMPA) from 2020 to 2023, specifically focusing on their characteristics, clinical evidence, and implementation effects. …”

Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx by Dan-Ni Yang (17642947)

“…This study aimed to investigate the influence of age and sex on the accuracy of CEA for differentiating MPE and benign pleural effusion (BPE).</p>Methods<p>We enrolled participants from a prospective cohort (SIMPLE) and a retrospective cohort (BUFF). …”

Supplementary file 1_Effects of nitrogen addition on SOC in alpine grasslands of the Qinghai-Tibetan Plateau and adjacent mountain regions: a meta-analysis.docx by Yanhui Ye (22775894)

“…However, long-term additions promote C loss via soil acidification and a critical shift in the microbial community, notably a decreased fungal-to-bacterial ratio. …”

Supplementary file 1_Wearable-derived heart rate variability and sleep monitoring as predictors of mood episodes in bipolar disorder: a case report.jpg by Aiko Eto (22769225)

“…Background<p>Bipolar disorder is a chronic psychiatric condition characterized by alternating episodes of mania and depression, and the prediction and management of mood episodes remain significant clinical challenges. …”

Data Sheet 1_Integrating groundwater pumping data with regression-enhanced random forest models to improve groundwater monitoring and management in a coastal region.pdf by Jamie Kim (14893220)

“…The predicted WTD anomalies align well with observations, with a test Nash-Sutcliffe Efficiency (NSE) of 0.49, a test Pearson correlation coefficient (r) of 0.72, and a test root-squared mean error (RMSE) of 1.61 m. …”

Table 2_Promotion of physical activity-related health competence using digital workplace-based health promotion: a pilot study for office workers.docx by Leonard Oppermann (20639363)

“…The other sub-competences also increased, but not significantly. HEPA decreased after the intervention and at follow-up, but the decrease was not statistically significant.…”

Image 1_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Table 3_Promotion of physical activity-related health competence using digital workplace-based health promotion: a pilot study for office workers.xlsx by Leonard Oppermann (20639363)

“…The other sub-competences also increased, but not significantly. HEPA decreased after the intervention and at follow-up, but the decrease was not statistically significant.…”

Table 1_Promotion of physical activity-related health competence using digital workplace-based health promotion: a pilot study for office workers.docx by Leonard Oppermann (20639363)

“…The other sub-competences also increased, but not significantly. HEPA decreased after the intervention and at follow-up, but the decrease was not statistically significant.…”

Image 2_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX by Ji Zeng (4336561)

“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”

Tobacco and alcohol use are the risk factors responsible for the greatest burden of head and neck cancers: a study from the Global Burden of Disease Study 2019 by Yue Yuan (113839)

“…Interestingly, the ASIRs for laryngeal cancer showed a decreasing trend over the studied time frame from 1990 to 2019. …”

Table 1_Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework.docx by Rajamohanan Pillai Ranith (22589207)

“…</p>Results<p>Results indicated a significant increase in built-up area (~12 Km2) near high-impact sites (Devipattinam, Thondi), versus ~4 Km2 increase at low-impact sites (Pamban and Mandapam North). …”

Supplementary Material for: Longer term outcomes of laparoscopic peritoneal lavage in the management of acute Hinchey III perforated diverticulitis: A Systematic review and Meta-An... by Sciascia D. (20480867)

“…There was significantly decreased likelihood of having a stoma in the LPL group however there was also a significantly increased likelihood of having recurrent diverticulitis. …”

Table 3_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.docx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 2_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 1_Biochar one-off application for paddy soil 15N loss improvement: evidence from a two-year experiment.docx by Jiping Gao (3816001)

“…In the first year, the N recovery efficiency (NRE) in N1C2 treatment decreased by 55.2%, 44.0%, and 21.4% for base, tiller, and panicle fertilizers, respectively, compared to and N2C1 decreased the NRE of the base fertilizers by 27.9% in the following year. …”

Image 1_Biochar one-off application for paddy soil 15N loss improvement: evidence from a two-year experiment.tif by Jiping Gao (3816001)

“…In the first year, the N recovery efficiency (NRE) in N1C2 treatment decreased by 55.2%, 44.0%, and 21.4% for base, tiller, and panicle fertilizers, respectively, compared to and N2C1 decreased the NRE of the base fertilizers by 27.9% in the following year. …”

Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…Melatonin, a hormone with antioxidant and immunomodulatory properties, has previously been shown to inhibit Japanese encephalitis virus (JEV) replication through RhoA pathway modulation.…”