Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Endoplasmic reticulum stress-related gene (ERSG) plays an indispensable role in the progression and immunotherapy of COAD. In this study, we evaluated the prognostic value of ERSGs in COAD.…”

Image 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Endoplasmic reticulum stress-related gene (ERSG) plays an indispensable role in the progression and immunotherapy of COAD. In this study, we evaluated the prognostic value of ERSGs in COAD.…”

<b>Association between myristic acid in plasma triglycerides and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: A comprehensive analysis... by Shigero Hosoe (21735020)

“…After comprehensive diabetes treatment for 2 weeks, FA levels in many TGs significantly decreased; especially, FA 14:0 levels in TGs decreased notably, and this reduction was more pronounced in patients with MASLD.…”

Deletion of glycosyltransferase <i>galE</i> impairs the InlB anchoring and pathogenicity of <i>Listeria monocytogenes</i> by Xiaowei Fang (696967)

“…We found that <i>galE</i> deletion reduced InlB anchoring, weakened bacterial adhesion and invasion of Caco-2 cells (human colorectal adenocarcinoma cells) and MGC803 cells (human gastric carcinoma cells), increased phagocytosis but decreased proliferation in RAW264.7 cells (mouse mononuclear macrophage leukaemia cells), and decreased bacteria load, mortality, and tissue damage in infected mice. …”

Data Sheet 1_Genetic variation in RYR1 is associated with heart failure progression and mortality in a diverse patient population.docx by Leonardo A. Guerra (20762270)

“…Based on eQTL data, these SNPs were associated with decreased RYR1 expression in vascular tissue. Two missense variants, in linkage disequilibrium with rs2915950 (rs2915952 and rs2071089) were significantly associated with decreased mortality risk (P = 0.03) and decreased risk of atrial fibrillation/flutter (OR: 0.66, 95% CI: 0.44–0.96; P = 0.03 and OR: 0.67, 95% CI: 0.45–0.98; P = 0.04, respectively). …”

Table 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.doc by Chanchan Xiao (9522614)

“…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”

Data Sheet 2_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.docx by Waner Wang (17773704)

“…By integrating expert consensus and hierarchical analysis, we have developed a novel framework tailored to China’s healthcare needs. …”

Data Sheet 1_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.pdf by Waner Wang (17773704)

“…By integrating expert consensus and hierarchical analysis, we have developed a novel framework tailored to China’s healthcare needs. …”

Image 2_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif by Chanchan Xiao (9522614)

“…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”

Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale by figshare admin karger (2628495)

“…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …”

Image 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif by Chanchan Xiao (9522614)

“…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx by Qingqing Zhuang (22109089)

“…Visual field mean deviation improved from −22.4 dB to −2.0 dB (p = 0.008). …”

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx by Chunmei Wu (3202050)

“…By week 48, 37.5% achieved DORIS remission, 32.1% LLDAS, and 19.6% remained clinically stable. Mean SLEDAI-2K decreased from 11.75 ± 9.31 (range: 0 to 46) to 1.45± 1.93 (range: 0 to 8). …”

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry by Bernhard L. Gerber (10171583)

“…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…”

Ultimate Lateral resistance of Tetrapod Pile Foundation in Rate-dependent and Strain-softening Clay by Zi-hao Zhao (21085578)

“…The effect of the reciprocal of soil sensitivity is more significant, while the strain rate <b>exhibits</b> a linear positive interaction with the ultimate lateral resistance. …”

Supplementary Material for: Anti-Vascular Endothelial Growth Factor Treatment Outcomes in Macular Telangiectasia: A Systematic Review by figshare admin karger (2628495)

“…In non-proliferative MacTel, mean CMT changed from 201 (32) µm to 199 (29) µm. …”

Glia-targeted 5-HT_2A receptor expression in adults reopens experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…All the individual data points are shown with the mean ± SEM. Significance is indicated as <i>p</i> < 0.0001 (****) and <i>p</i> > 0.05 (not significant, ns). …”

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…”