Structure–Activity Relationships of Azaquinazolinone Derivatives as ¹⁸F‑Labeled PET Probes Targeting Ghrelin Receptors by Hiroyuki Watanabe (312793)

“…Among them, AQ-12 showed the highest binding affinity for GHSR. In a biodistribution study using normal mice, [¹⁸F]AQ-12 displayed high uptake in the pancreas, which is one of the GHSR-expressing organs, and its radioactivity was significantly decreased by coinjection with unlabeled AQ-12. …”

<i>Kif15</i> deficient mice exhibit both depressive and manic behaviors in adulthood. by Xiaomei He (795333)

<i>Kif15</i> deletion results in abnormal distribution of PSD95 in neuropil. by Xiaomei He (795333)

<i>Kif15</i> deficiency affects the expression of Gephyrin and GABRB1 in PFC and hippocampus. by Xiaomei He (795333)

Comparisons of mean values of lipid profiles of <i>H</i>. <i>pylori</i>-infected and non-infected study participants at Jimma Medical Hospital, 2023. by Negussie Sarbecha (20108068)

<i>Kif15</i> deficiency affects the expression of excitatory postsynaptic receptors in PFC and hippocampus. by Xiaomei He (795333)

“…<p><b>(A and D)</b>: Western Blot analysis showed decreased protein levels of PSD95 and NMDA receptor GluN2A in the PFC of 3 week-old <i><i>Kif15</i></i>^<i>-/-</i> mice, n = 7 ~ 8 in <i><i>Kif15</i></i>^<i>+/+</i> group, n = 6 in <i><i>Kif15</i></i>^<i>-/-</i> group. …”

Characteristics of study subjects. by Jung Eun Choi (563339)

“…There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations.…”

Graded loading creep stress loading level. by Dengke Yang (842532)

“…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …”

Schematic diagram of rock samples. by Dengke Yang (842532)

“…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …”

Rock mechanics testing machine. by Dengke Yang (842532)

“…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …”

Results of SD-TOPSIS application ‐ combination A. by Roman Vavrek (13200141)

“…Based on the performed analyses, we can see that significant differences result from their reduction. …”

<i>Kif15</i> deficiency leads to impaired development of dendritic spines in PFC and hippocampus of mice. by Xiaomei He (795333)

Data Sheet 1_Prehospital tranexamic acid decreases early mortality in trauma patients: a systematic review and meta-analysis.docx by Yi Li (1144)

“…</p>Conclusion<p>Prehospital TXA decreases early (24-h) mortality in trauma patients without a significant increase in the risk of VTE and other complications, and further studies are still needed to improve and optimize its management strategy.…”

The role of LytA in functionally linking decreased NAM <i>O-</i>acetylation with <i>hsdS</i> inversions and colony phase. by Xiu-Yuan Li (3328056)

The requirement of LytA-associated proteins for linking decreased NAM <i>O-</i>acetylation with the orientations of <i>hsdS</i> inversions. by Xiu-Yuan Li (3328056)

Postnatal death of <i>aP2-Drp1</i>^f/f neonatal mice. by Yuta Ibayashi (20404811)

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

Loxoprofen and SB225002 administration decreased sound stress exposure-induced hyperalgesia. by Satoka Kasai (3861115)

“…Mice treated with loxoprofen (500 mg/kg) or SB225002 (3 mg/kg) showed significantly decreased response times to the filament compared to Stress + saline group (Stress + loxoprofen (500 mg/kg), 30 min after administration, **<i>P</i> < 0.01, 60 min after administration, ***<i>P</i><i> <i><</i> </i>0.001; Stress + SB225002 (3 mg/kg), 60 min after administration, *<i>P</i> < 0.05). 2-way ANOVA <i>post-hoc</i> Bonferroni test. …”