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6381
Data Sheet 1_Impact of the SARS-COV-2 pandemic on access to health services in Angola: a focus on diagnosis and treatment services for tuberculosis.docx
منشور في 2025"…</p>Results<p>There was a significant decline in access to TB services during the pandemic, with a substantial decrease in reported cases (−15.5% in 2020; −18.3% in 2021) and treatment rate (from 86% in 2019 to 68% in 2020), an increase in multidrug-resistant-TB (from 0.2% in 2018 to 2.1% in 2022) and TB/HIV co-infections (from 6% in 2018 to 8.8% in 2021). …"
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6382
DataSheet1_Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.docx
منشور في 2024"…Among the 620 patients in both groups, 57.42% demonstrated good adherence (≥80%) at 3 months; this percentage dropped to 31.45% at 6 months. At 3 months of observation, the percentages of patients demonstrating good adherence were significantly different between the groups (64.52% in the PGxT group vs. 50.32% in the TAU group; p < 0.001). …"
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6383
Supplementary Material for: Evolution of growth following anti-TNF-α therapy in paediatric Crohn’s disease: data from the Swiss IBD Cohort Study
منشور في 2025"…Height velocity z-scores showed a significant increase across both genders. Factors contributing to a decreased height z-score included male sex, age 10 and below at diagnosis, a concomitant corticosteroid treatment and a top-down treatment strategy. …"
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6384
Experience-dependent and temporally restricted serotonin signaling and synaptic glomeruli pruning.
منشور في 2024"…All the individual data points are shown with mean ± SEM. Significance is indicated as <i>p</i> < 0.0001 (****) and <i>p</i> > 0.05 (not significant, ns). …"
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6385
Reduced expression of MYBPC3 mRNA and cMyBP-C protein in the proband.
منشور في 2025"…<p>(A) RT-qPCR analysis showing significantly decreased MYBPC3 mRNA levels in cardiac sample from the proband compared to control subjects. …"
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6386
Table 1_Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences.docx
منشور في 2025"…</p>Results<p>Among the 191 participants (mean age 48.94 years, 68.06% male) included in the study, 83.77% had OSA. …"
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6387
Mapping changes in patterning after inhibition of Notch activity.
منشور في 2025"…Note the statistically significant decrease in the CLE and NSB like regions TBX6. …"
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6388
Table 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.xlsx
منشور في 2025"…ORes inhibited breast cancer cell growth, increased intracellular ferrous ion levels, reactive oxygen species, and lipid peroxidation, and induced ferroptosis-related mitochondrial alterations. These effects were associated with decreased GPX4 expression and suppression of EGFR, phosphorylated PI3K, and phosphorylated AKT. …"
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6389
Data Sheet 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.pdf
منشور في 2025"…ORes inhibited breast cancer cell growth, increased intracellular ferrous ion levels, reactive oxygen species, and lipid peroxidation, and induced ferroptosis-related mitochondrial alterations. These effects were associated with decreased GPX4 expression and suppression of EGFR, phosphorylated PI3K, and phosphorylated AKT. …"
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6390
Table 1_MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells.xlsx
منشور في 2025"…</p>Results<p>Our results have indicated that miR-216a-3p has higher expression in NK cells of patients with HCC, and simulating this elevated expression pattern via forcing miR-216a-3p expression in normal NK cells has negatively impacted the release of TNF- α, IFN- γ, GrB, and PRF. Consequently, a decrease in cell cytolysis was observed. Our in silico analysis revealed that the predicted downstream targets of miR-216a-3p are enriched in the FOXO-signaling pathway. …"
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6391
Table 1_Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study.docx
منشور في 2025"…Across groups, IC-related activity was observed in bilateral fronto-cortico-striatal circuitry, including dorsal striatum (DS) and dorsal/supragenual anterior cingulate cortex (dACC). …"
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6392
Table 3_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.docx
منشور في 2025"…</p>Results<p>Splenic white pulp disorganization was observed in most animals, indicating marked tissue disruption. …"
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6393
Table1_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.xlsx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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6394
Table2_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.docx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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6395
Table 1_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.docx
منشور في 2025"…</p>Results<p>Splenic white pulp disorganization was observed in most animals, indicating marked tissue disruption. …"
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6396
Table3_Microbe-immune interactions: new perspectives on coagulation deficiencies, purpura, and other hemorrhagic conditions under the regulation of the gut microbiota.xlsx
منشور في 2024"…The mediating effect is opposite to the overall trend and has a relatively small impact. No significant heterogeneity or pleiotropy was observed.…"
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6397
Table 2_Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study.docx
منشور في 2025"…Across groups, IC-related activity was observed in bilateral fronto-cortico-striatal circuitry, including dorsal striatum (DS) and dorsal/supragenual anterior cingulate cortex (dACC). …"
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6398
Table 2_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.docx
منشور في 2025"…</p>Results<p>Splenic white pulp disorganization was observed in most animals, indicating marked tissue disruption. …"
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6399
Image 1_Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis.jpg
منشور في 2025"…</p>Results<p>Splenic white pulp disorganization was observed in most animals, indicating marked tissue disruption. …"
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6400
Flow Chart of the Study Steps.
منشور في 2025"…The data were analyzed using descriptive tests (mean, standard deviation, and percentage) and analytical tests (including ANCOVA and Student T-test).…"