Comparison of opioid use among long-term care residents in Ontario and Alberta, Canada: A multi-jurisdictional, repeated cross-sectional study by Colleen J. Maxwell (3818041)

“…In both provinces, there were significant decreases in higher risk opioid prescribing over time, including concurrent use with benzodiazepines, but also significant increases in the concurrent use with gabapentinoids and tramadol use (Alberta only).…”

Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

“…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19⁺ B cells and CD14⁺ monocytes, but significantly decreased on CD56⁺ NK cells.We identified a distinct CD226⁺CD19⁺ B cell subset that exhibited pathogenic features in pSS. …”

Table 1_Nonlinear pathological trajectory of a high-myopia C57/BL6J mouse model induced by form deprivation.xlsx by Yue Wen (1673968)

“…Retinal vascular area proportion in covered eyes decreased significantly (P < 0.05), with a decline rate of 11% from weeks 4 to 8 and a faster decline of 19% from weeks 8 to 12, while this proportion increased significantly in control eyes.…”

Figure 3 from A Proteomic Signature for Human Papillomavirus–Associated Oropharyngeal Squamous Cell Carcinoma Predicts Patients at High Risk of Recurrence by Christopher C. Jackson (21027397)

“…<p>Differential abundance of 233 unique protein groups identified from 405 DAPeps discriminates R from NR. <b>A,</b> Volcano plot shows the distribution of 233 proteins significantly up- or downregulated in the R relative to NR in samples of patients with HPV+OPSCC. …”

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…<p>Visceral leishmaniasis (VL), the most severe form of leishmaniasis, remains a significant public health concern that cannot be overlooked in underdeveloped regions. …”

Table 1_Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study.docx by Alissa Behn (20793590)

“…Among these, significant concentration differences were observed for TIMP-2, TGF-ß₃, and complement component C3 between the filtered and unfiltered samples. …”

Table 4_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

DataSheet1_Effects of total flavonoids of Rhizoma Drynariae on biochemical indicators of bone metabolism: a systematic review and meta-analysis.DOCX by Wei Li (7081)

Table 2_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

“…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”

Table 3_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

Table 1_Association between cardiovascular health and markers of liver function: a cross-sectional study from NHANES 2005–2018.docx by Huang Yu (5882174)

“…</p>Results<p>Linear regression analysis showed that each 1-point increase in CVH score was significantly associated with decreased levels of liver enzymes [ALT: −0.200 U/L (95% CI: −0.223, −0.176), AST: −0.043 U/L (−0.062, −0.024), GGT: −0.453 U/L (−0.509, −0.397), ALP: −0.310 U/L (−0.340, −0.281)] and increased levels of albumin [0.040 g/dL (0.036, 0.045)] and AST/ALT ratio [0.0056 (0.0051, 0.0061)]. …”

Table 1_Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study.docx by Michael Sayer (11493436)

“…</p>Results<p>PhenoAge and GrimAge demonstrated significant age acceleration relative to non-cancer controls and worsening cognitive function symptoms, with accelerated GrimAge associated with decreasing BDNF levels. …”

Table 2_Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study.docx by Michael Sayer (11493436)

“…</p>Results<p>PhenoAge and GrimAge demonstrated significant age acceleration relative to non-cancer controls and worsening cognitive function symptoms, with accelerated GrimAge associated with decreasing BDNF levels. …”

Data Sheet 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.doc by Junjie Liu (193511)

“…For other outcomes, including gestational diabetes mellitus, ectopic pregnancy, placental abruption, placenta previa, large and small for gestational age, preterm birth, high and low birth weight, perinatal death, stillbirth, neonatal death, and congenital anomalies, no significant disparities were observed.</p>Conclusions<p>Donor sperm offers improved pregnancy outcomes for severe male infertility or paternally inherited genetic disorders but is linked to elevated risks of preeclampsia and pregnancy-induced hypertension. …”

Table 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.xlsx by Yan Wang (15435)

“…Median survival durations decreased progressively: 716 days (mild), 362 days (moderate), and 106 days (severe). …”

Image 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.tif by Yan Wang (15435)

“…Median survival durations decreased progressively: 716 days (mild), 362 days (moderate), and 106 days (severe). …”

Ambient Air Pollutant Dynamics (2010–2025) and the Exceptional Winter 2016–17 Pollution Episode: Implications for a Uranium/Arsenic Exposure Event by Thomas Clemens Carmine (19756929)

“…PM₁₀ also shows a general decrease. CO appears relatively more stable.…”

Clinical and epidemiological data of patients. by Mailma Costa de Almeida (22057684)

“…CTG showed a significant reduction in pain within 24 hours in the per-protocol analysis (Log-rank <i><i>p</i></i> = <i><i>0.04</i></i>). …”

Data Sheet 5_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf by Yi-Ming Ren (555968)

“…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …”