Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”

A bar graph showing the overall colony loss rates and 95% confidence intervals for the 1,786 beekeepers interviewed across the nine Sub-Saharan African countries. by Beatrice T. Nganso (4114768)

Results of redundancy analysis. by Bianhua Zhang (22430652)

“…<div><p>In order to clarify the effects of long-term coal gangue(CG) dump on the surrounding soil bacterial community structure, we selected the CG dump formed during the mining of Tunlan coal mine in Gujiao city, Shanxi province in China as the study area to conduct a comprehensive study, the experimental design included six distinct zones: control soil area with no impaction (NC), undisturbed control sediment area (NL), atmospheric dry and wet deposition area (MC), upstream (MLS), midstream (MLZ) and downstream (MLX) in the leachate flow area (LFA), Using high-throughput sequencing technology and related software analysis, we obtained the following key findings: The heavy metal contents of Cr and Cd were different significantly in MC and NC (p < 0.05),Cr (90.18 mg·kg-1) in MC was higher than that in NC (65.29 mg·kg-1) (p < 0.05), while Cd (0.09 mg·kg-1) was lower than that in NC (0.14 mg·kg-1) (p < 0.05), and there was no significant differences in Cu, Zn, As and Pb between MC and NC (p > 0.05). …”

Association of covariates and COPD risk. by Yushan Shi (16440272)

“…Stratified analyses revealed no significant differences or interactions.</p><p>Conclusion</p><p>Our findings suggest a potential link between increased dietary niacin intake and a decreased prevalence of COPD.…”

The effect of β-blocker treatment on renin (A) and aldosterone-to-renin ratio (B). by Ningning Wang (560944)

A brief illustration of the revisions between AJCC TNM eighth and ninth editions. by Aihong Zheng (20571034)

Average Time Between Successive R-wave Peaks (RR Intervals) across pre-interview, interview and post-interview phases for High and Low Clarity and Authority groups: RR decreases fr... by David Vagni (8060432)

Videofluoroscopic swallowing study parameters. by Rie Asayama (693361)

“…Histological analysis demonstrated marked variability in muscle fiber size and a high frequency of central nuclei. Additionally, decreased expression of chloride channel 1 was observed in the masseter muscle, suggesting the presence of myotonia. …”

The shortened version of the Edinburgh Handedness Inventory encompasses 4 items (e.g. writing) scored on a 5-point scale ranging from:” Always right; usually right; both equally; u... by Marcel F. Hinss (14675457)

LncRNA <i>C5orf64</i> polymorphisms (rs12518552 and rs2950218) decreases pulmonary tuberculosis susceptibility by Shilin Xu (1884217)

Image1_Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality.tif by Yi Zhang (9093)

“…Furthermore, when stratified by sleep duration, moderate to severe depression group showed a great decrease in progressive motility (PR), total motility, concentration and total sperm count (TSC) as referred to normal group in participants with sleep duration less than 7 hours.…”

Deficiency of <i>Irg1</i> decreased lung neutrophils in mice during <i>M</i>. <i>pneumoniae</i> infection. by Cui Wang (141700)

<i>Oenocarpus bacaba</i> palm tree (A) and fruit (B). by Eudes Alves Simões-Neto (19697968)

“…Serological cure was achieved in 34.6% of cases, and IgG titers decreased in 15.3%.</p><p>Conclusions and significance</p><p>We encountered several barriers in managing ACD, including population vulnerability, reliance on outdated diagnostic techniques, lack of standardized molecular biology methods, and limited therapeutic options. …”

<i>IRF1</i> impacts VACV replication in glucose/IFN-γ primed but not galactose conditions. by Tyron Chang (9922533)

Ingenuity pathway analysis of tonic ISG subclasses. by Tyron Chang (9922533)

Analysis of host and interferon-induced responses in glucose/galactose infected with vaccinia virus. by Tyron Chang (9922533)

Vaccinia virus and VSV infections of <i>STAT1</i> and <i>IRF1</i> KO cells grown in glucose/galactose with and without IFN-γ priming. by Tyron Chang (9922533)

Glucose but not galactose culturing of IFN-γ primed cells reduces VACV and HSV-1 replication. by Tyron Chang (9922533)

Glucose/galactose selectively alters ISG protein not RNA levels in interferon-primed cells. by Tyron Chang (9922533)

related to Fig 5. (A) the total number of eggs in the livers did not differ between BL/6 and Gsdmd-/- mice. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

“…Data are representative of two independent experiments. Significance was determined using a Student’s t-test ***p < 0.0005.…”