Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Table 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx by Zhengqing Yu (12641890)

“…Compared with individuals with a low level of circulating GDF-15, those with high GDF-15 level had a higher prevalence of hypertension [odds ratios (OR) 1.60, 95% confidence interval (CI) 1.37–1.88, P < 0.001). …”

Burden trends and risk factors for prostate cancer from 1990 to 2021: a systematic analysis of the Global Burden of Disease Study 2021 by Yuan Xu (161775)

“…PCa was more common in regions with a high SDI. Mortality was the highest in regions with a low SDI. …”

Data Sheet 1_Donor's therapeutic hypothermia vs. normothermia in kidney transplantation: a meta-analysis of randomized controlled trials.pdf by Luccas Marcolin Miranda (20991023)

“…When excluded from the analysis, a significant reduction in DGF rate was observed among the hypothermia-treated group (RR 0.80; 95% CI 0.67–0.94; P = .007).…”

Supplementary Material for: Safety profile of intravitreal Dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies. by figshare admin karger (2628495)

“…In general, the peak IOP increase was typically observed 60 days post-DEX-i injection, followed by a decrease in the subsequent months. In most patients, these IOP-related AEs were successfully and efficiently managed with topical IOP-lowering medication, although some patients required additional treatments (i.e., laser or surgery). …”

Table 1_The role of gut microbiota in modulating immune responses in chronic liver disease: a systematic review and meta-analysis.docx by Eyad Gadour (21375983)

“…The findings revealed that gut microbiota-modulating therapies significantly reduced tumor necrosis factor-α (TNF-α) levels compared to control interventions (standardized mean difference [SMD], -0.60; 95% confidence interval [CI] [-0.93, -0.23] p = 0.001), with similar results observed at the 6-month follow-up (SMD -1.3; 95% CI [-2.1, -0.4] p = 0.004). …”

Image4_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 1_Individualization of clinical target volume delineation in eccentric nasopharyngeal carcinoma: a prospective comparative study.docx by Yunrui Song (10672668)

“…</p>Results<p>Our results showed that compared with conventional CTV, the volume of CTV decreased significantly (P< 0.05) through individualizing delineation for eccentric NPC, especially CTV1 volume (95.81 cm³ vs. 57.57 cm³, P < 0.001). …”

Image2_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_A population-based study of social demographic factors, associated diseases, and herpes zoster ophthalmicus in Taiwan.docx by Chia-Yi Lee (2037286)

“…</p>Results<p>Patients with systemic diseases (hypertension, diabetes, hyperlipidaemia, etc.) had significantly higher ORs for HZO development. Patients whose monthly income was >NT$ 30,000 and patients residing in southern Taiwan had increased odds of developing HZO; however, patients residing in northern Taiwan, metropolitans, or satellite cities, and being public servants (military, civil, teaching staff, etc.) had decreased odds of developing HZO.…”

Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Data Sheet 1_What should we focus on in pregnancy complicated by pheochromocytoma? a bibliometric analysis (1990-2024).pdf by Shiyun Deng (21734750)

“…Purpose of review<p>The incidence of pheochromocytoma and paraganglioma (PPGL) in pregnancy is extremely low, yet it poses a significant threat to maternal and fetal safety. …”

Image3_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Table1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.docx by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx by Lillia A. Baird (10575941)

“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”

Image 1_iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis.tif by Jingyu Zhao (2371618)

“…Background<p>Cryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. …”

Table 2_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx by Cindy E. Frias (20899853)

“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”

Table 1_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx by Cindy E. Frias (20899853)

“…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…”