The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model by Zichen Huang (6587885)

“…The IRF-1–associated gene–based machine learning model provides a robust, noninvasive diagnostic tool.</p>…”

Supplementary Material for: Preoperative prediction of microvascular invasion in intrahepatic cholangiocarcinoma and its prognostic implications: A multicenter study by figshare admin karger (2628495)

“…Stratifying patients by MVI risk—low (no predictors), intermediate (1–3 predictors), and high (4 predictors)— revealed a significant decrease in both recurrence-free and overall survival rates (p<0.001), along with a corresponding increase in early recurrence rates (p<0.001) as the risk level increased. …”

The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis by Guowen Zhao (19775328)

“…<p>Gastrointestinal bleeding is an important gastrointestinal complication among peritoneal dialysis patients and correlated with a higher risk of mortality. Increased uric acid levels are a significant complication for peritoneal dialysis patients and have been associated with an increased risk of hemorrhagic stroke. …”

Efficacy and safety of anticoagulation in asymptomatic cirrhotic patients with portal vein thrombosis: a systematic review and meta-analysis by Qingping Wu (789611)

“…Compared to no intervention, anticoagulation significantly increased the PVT recanalization rate (OR = 3.89, <i>p</i> < .001) and decreased the PVT progression rate (OR = 0.28, <i>p</i> < .001) as well as overall mortality (OR = 0.66, <i>p</i> = .008). …”

RBM39 is methylated by PRMT6 at arginine 92. by Tongjia Zhang (16496661)

Table 1_The effectiveness of exercise interventions in the improvement of sleep in older adult people: a meta-analysis.docx by Di Geng (1681915)

“…Background<p>Sleep problems are prevalent among the older adult population, with a significant impact on their health and overall well-being. …”

Parameters of VMR separated by light or dark periods run at 6 dpf. by Morgan Barnes (7876373)

“…(I-K) VMR parameters in dnVDRa induced zebrafish at 72 hpf. There is a significant decrease in distance moved (p < 0.05), a significant decrease in velocity the light period (p < 0.05) and a significant decrease in activity state in the light periods (p < 0.05) in the 72 + fish. …”

Data Sheet 1_Factors affecting posaconazole plasma concentrations: a meta-analysis and systematic review.docx by Ruochen Qu (16946790)

“…High-fat meals, age, and sex did not have a significant impact on posaconazole oral suspension (POS) concentrations. …”

Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx by Yi-Ting Sun (4691629)

“…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …”

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…VMAT significantly improved the V₃₀ of PTV-brain-SIB (p<0.001), decreased HI (p=0.003), and increased CI (p<0.001). …”

<b>Fire Severity Alters Soil Microbial Diversity and Community Stability in a Subtropical Forest Ecosystem</b> by Xuezhao (21803957)

“…Moreover, low-severity fires increased the functional taxa associated with chemoheterotrophic and aerobic chemoheterotrophic bacteria, whereas the ectomycorrhizal fungi was significantly reduced in fired plots. Network analysis indicated that the complexity and connectivity of microbial networks gradually decreased with increasing fire severity.…”

Visual motor response assay at 28 dpf. by Morgan Barnes (7876373)

“…(E-H) VMR parameters in dnVDRa induced zebrafish at 48 hpf. There is a significant decrease in distance moved in the dark period (p < 0.05), a significant decrease in velocity in the dark (p < 0.05) and light (p < 0.01) periods, a significant decrease in activity state in the dark period (p < 0.001) and light period (p < 0.01) and a significant decrease in distance to point in the dark period (p < 0.05) and light period (p < 0.05) in the 48 + fish. …”

Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc by Hua Chai (280388)

“…<p>Carbon (C) fluxes in semiarid grasslands subject to precipitation variability play a critical role in the terrestrial C cycle. However, how ecosystem C fluxes respond to variability in precipitation (both decreases and increases precipitation along a gradient) remains unclear. …”

Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx by Jianzu Wu (13935369)

“…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …”

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

Data Sheet 1_Comparative efficacy and safety of antidiabetic agents for post-transplant diabetes mellitus: a network meta-analysis.docx by Shanbiao Hu (15063765)

“…Compared to placebo, insulin produced the greatest reductions in HbA1c (mean difference [MD] − 0.35, 95% CI − 0.90 to 0.20) and FPG (MD − 9.06 mmol/L, 95% CI − 18.66 to 0.53). …”

The Patient Global Impression of Change as a complementary tool to account for neurobehavioral and mental health symptom improvement for patients with concussion by Rosemay A. Remigio-Baker (7864583)

“…</p> <p>Higher PGIC scores were related to a higher prevalence of clinically-relevant <i>decrease</i> in NSI, PCL-5 or PHQ-8 scores. …”

<i>IRF1</i> impacts VACV replication in glucose/IFN-γ primed but not galactose conditions. by Tyron Chang (9922533)

Ingenuity pathway analysis of tonic ISG subclasses. by Tyron Chang (9922533)