Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents by Chaoquan Tian (21009122)

“…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …”

Effects of injury on exploratory behavior. by Ella R. Dockendorf (21533334)

Livestock–Crop–Mushroom (LCM) Circular System: An Eco-Friendly Approach for Enhancing Plant Performance and Mitigating Microbiological Risks by Dong Liu (115204)

“…Mushroom production using agroforestry biowaste is a great green cycling agriculture alternative. …”

Retention and extinction of operant learning. by Ella R. Dockendorf (21533334)

Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx by Li Zhang (8200)

“…</p>Conclusions<p>Results suggest that a daily positive work reflection intervention is a feasible and promising intervention for decreasing Chinese nurses' psychological distress. …”

Image 1_A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis.jpeg by Michael R. Kann (22070273)

“…Across studies, the primary risk of bias was due to confounding variables, resulting in a serious risk of bias in 12 studies (48.0%).</p>Discussion<p>Kyphoplasty provides comparable outcomes in thoracic and lumbar VCFs, with no clinically significant differences in pain relief or procedural effectiveness. …”

Table 1_A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis.docx by Michael R. Kann (22070273)

“…Across studies, the primary risk of bias was due to confounding variables, resulting in a serious risk of bias in 12 studies (48.0%).</p>Discussion<p>Kyphoplasty provides comparable outcomes in thoracic and lumbar VCFs, with no clinically significant differences in pain relief or procedural effectiveness. …”

Catalytic CO₂ Capture Performance of a MEA-EAE-DEEA Trisolvent in a Hot Silicon Oil-Based Pilot Plant by Yu Li (183836)

“…To implement an energy-efficient combination of CO₂ capture technology, the pilot plant studies were conducted in preparation of commercialization of CCUS demonstration plants, during which a set of specific amine blends with various catalytic packing was employed. …”

Data Sheet 1_A comprehensive examination and analysis of the effectiveness and safety of finerenone for the treatment of diabetic kidney disease: a systematic review and meta-analy... by Jianyu Chen (2624254)

Table 1_Efficacy and safety of combination of frankincense and botulinum toxin in the treatment of blepharospasm: a protocol for a single-centre, open-label, randomized, controlled... by Shiyuan Gong (22754579)

“…Symptom improvement is defined as a decrease of one point or more in the Jankovic Rating Scale severity score compared to baseline in patients with BSP. …”

Supplementary file 1_MoodyTunes: a single cohort study of a music-based smartphone app for mental health and mood regulation in young people.pdf by Sandra Garrido (485995)

“…Depression was found to have decreased, although not at a statistically significant level. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”

Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx by Elisa Barbieri (115023)

“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”

Data Sheet 1_Artificial intelligence–enhanced mapping of the international classification of functioning, disability and health via a mobile app: a randomized controlled trial.zip... by Zhandos Kurban (21985553)

“…A total of 185 adult inpatients (≥18 years) were randomized to either a control group using paper questionnaires or an experimental group using the MedQuest app. …”

Developmental change in 5-HT_1A binding in known cause of death controls (predischarge and postdischarge combined). by Hannah C. Kinney (10280975)

“…Binding in these nuclei are visually (top row) and quantitatively (bottom row) decreasing with PC age, the latter shown with plots of 5-HT_1A binding vs PC age. …”

Electromagnetic torque ripple. by Abdelfattah Dani (22226715)

“…Analysis of the simulation results for the proposed control versus field-oriented control (FOC) shows that the proposed control strategy exhibits less ripples in the electromagnetic torque, with the ripple ratio decreasing significantly from 32.95% to 19.43%. In addition, the THDs of the stator current decreased from 20.87% to 14.88%, proving the reliability and efficiency of the proposed control strategy compared to FOC. …”

The evolution. by Abdelfattah Dani (22226715)

“…Analysis of the simulation results for the proposed control versus field-oriented control (FOC) shows that the proposed control strategy exhibits less ripples in the electromagnetic torque, with the ripple ratio decreasing significantly from 32.95% to 19.43%. In addition, the THDs of the stator current decreased from 20.87% to 14.88%, proving the reliability and efficiency of the proposed control strategy compared to FOC. …”

ANN architecture. by Abdelfattah Dani (22226715)

“…Analysis of the simulation results for the proposed control versus field-oriented control (FOC) shows that the proposed control strategy exhibits less ripples in the electromagnetic torque, with the ripple ratio decreasing significantly from 32.95% to 19.43%. In addition, the THDs of the stator current decreased from 20.87% to 14.88%, proving the reliability and efficiency of the proposed control strategy compared to FOC. …”