Data Sheet 2_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.docx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

Data Sheet 1_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.docx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

Land Use Change Transfer Diagram. by Wanzhuang Huang (17357306)

“…The impact of road network density and river network density on the evolution of production-living-ecological land conflicts in the Shiyang River Basin was the most significant. The optimization results of national spatial patterns and regulation strategies could provide a scientific basis for the optimization and comprehensive management of national spatial planning in arid inland river basins.…”

Research framework. by Wanzhuang Huang (17357306)

“…The impact of road network density and river network density on the evolution of production-living-ecological land conflicts in the Shiyang River Basin was the most significant. The optimization results of national spatial patterns and regulation strategies could provide a scientific basis for the optimization and comprehensive management of national spatial planning in arid inland river basins.…”

Image 2_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”

Image 1_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”

Supplementary file 1_Modulatory effects of transcranial direct current stimulation on sensory gating in Fibromyalgia Syndrome.docx by Juan L. Terrasa (5506691)

“…This modulation manifested as an increased difference in the right hemisphere (contralateral to the stimulation) and a decreased difference in the left hemisphere (ipsilateral).…”

The effects of emotional expressivity and self-efficacy levels of individuals with substance addiction on treatment compliance by Murat Toprak (19853862)

“…</p> <p>In the present study, the emotional expressivity total score average of the participants was found to be 26.53 ± 9.03, their self-efficacy/sufficiency total score average was 74.15 ± 14.84, and their treatment compliance total score average was 85.27 ± 17.25. A negative and significant relationship was detected between the TCS total score and the EES total score of the participants, and there was a positive and significant relationship with the SES total score average (<i>p</i> < .05).…”

Table 1_Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy.docx by Rui Su (822125)

“…Over 28 days of antifungal treatment, significant decreases in the CSF levels of IL-2 and IL-10 and the plasma levels of IL-10 and IL-4 were observed. …”

Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx by Yiting Tang (2295307)

“…Background<p>Type 2 Diabetes Mellitus (T2DM) poses a significant global health challenge, particularly among elderly adults. …”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…A one-compartment model was developed, with creatinine clearance (CrCL) and platelet count (PLT) identified as significant covariates influencing PK parameters. …”

Data_Sheet_1_Systematic analysis and prediction of the burden of lower respiratory tract infections attribute to non-optimal temperature, 1990–2019.docx by Yu Shi (117923)

“…BAPC model projections suggest a downward trend in the future burden of death and DALYs from the disease, but the improvement in the burden of death for women was not significant.…”

Table 1_Immediate effects of extracorporeal radial pressure wave therapy on dystonia, static plantar pressure distribution, and balance in patients with Parkinson’s disease.docx by Zhiqin Xu (524585)

“…</p>Results<p>After ERPWT, significant decreases were observed in muscle tone, stiffness, and elasticity of the achilles tendon on the more PD-affected side and the anterior aspect of the planta on both feet (p < 0.05). …”

Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm by figshare admin karger (2628495)

“…The angiopoietin–TIE2 receptor tyrosine kinase pathway plays a key role in regulating vascular homeostasis, but was previously overlooked as a target for rosacea therapy. …”

Dependent and independent variables (N = 316). by Priyanka Saluja (20501044)

“…<div><p>Introduction</p><p>Unmet oral health needs remain a significant issue among immigrant adolescents, often exacerbated by experiences of racial discrimination. …”

Protocol for our RNA-seq. by Sabih Rashid (5618807)

“…GO enrichment was conducted using the Wormbase Gene Set Enrichment Analysis [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref046" target="_blank">46</a>,<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref047" target="_blank">47</a>]. …”

Table 1_Outcomes of mini-monovision with monofocal, enhanced monofocal and extended depth-of-focus intraocular lenses.docx by Issac Levy (20762594)

“…</p>Conclusion<p>While enhanced monofocal and EDOF IOLs may provide slightly better binocular intermediate visual outcomes and higher spectacle independence compared to monofocal lenses with regards to mini-monovision and intermediate vision performance, the differences are not statistically significant. All three IOL types exhibit high patient satisfaction rates when choosing a mini-monovision approach with decreased dependence on spectacles.…”

Oxidative imbalance linked to impaired mitochondrial bioenergetics mediates the toxicity of mesoionic compounds MI-D and MI-J in hepatocarcinoma cells (HepG2) by Ana Paula Perbiche Neves (20978015)

“…MI-D in the HG medium decreased glutathione peroxidase (GPX) activity, whereas MI-J reduced the enzyme activity at a concentration of 25 μM and increased it at 50 μM. …”

Analysis of connexin 43 expression in mice inoculated intravenously with EVs (green) or ICs (blue). by Alberto Cornet-Gomez (10676133)

“…<p>Confocal microscopy revealed decreased connexin 43 synthesis in mice injected with EVs and ICs <b>(A)</b>. …”

Cilium disassembly defects were rescued with ectopic expression of CCDC66 but not CEP104. by Jovana Deretic (13113617)

“…(Welch <i>t</i> test <i>p</i> value ns: not significant). <b>(D)</b> IMCD3::CEP104-BirA*-Flag were transduced with control and CCDC66-targeting shRNA, selected and seeded on coverslips. …”