Showing 6,561 - 6,580 results of 17,906 for search 'significantly ((((largest decrease) OR (teer decrease))) OR (((nn decrease) OR (a decrease))))', query time: 0.47s Refine Results
  1. 6561

    Metrics formula [24]. by Mohammadreza Namdar (22439057)

    Published 2025
    “…Results demonstrate that the developed appraoch is highly accurate and significantly faster than manual classification, which can dramatically decrease software development time and cost.…”
  2. 6562
  3. 6563

    Baseline characteristics of participants. by Hyungjong Park (10147327)

    Published 2025
    “…In the multivariable Cox regression analysis, eGFR > 120 mL/min ∙ 1.73 m<sup>2</sup> was associated with a decreased risk of dyslipidemia (HR: 0.35; 95% CI [0.34–0.36]). …”
  4. 6564

    Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

    Published 2025
    “…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
  5. 6565

    Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

    Published 2025
    “…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
  6. 6566

    Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

    Published 2025
    “…In ovariectomized mice, <b>5cc</b> administration (5 mg/kg) improved the trabecular microarchitecture, bone mineral density, and strength, at levels comparable to teriparatide, while significantly reducing bone resorption markers. With 13.57% oral bioavailability and selectivity for PDE1A1 (32% inhibition at 500 nM), <b>5cc</b> offers an innovative therapeutic candidate for PMO with a dual anabolic-antiresorptive profile and oral efficacy, warranting further clinical development.…”
  7. 6567

    RSA results across a broader frequency band (0.1–150 Hz). by Pengcheng Lv (7609706)

    Published 2025
    “…<p><b>(A)</b> For the translation epochs from good trials, the similarity of Same Context was significantly greater than the similarity of Different Context in HC. …”
  8. 6568

    Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria... by Huaxiang Liu (322464)

    Published 2025
    “…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”
  9. 6569
  10. 6570

    Molecular Logic Gate for Sensing pH/Peroxynitrite with Potential Applications in Cisplatin Treatment by Lifang Guo (1460884)

    Published 2024
    “…With this probe, the significant roles of pH and ONOO<sup>–</sup> in cisplatin treatment are disclosed, in which the cell account shows a dramatic reduction accompanied by decreased pH and upregulated ONOO<sup>–</sup> levels. …”
  11. 6571

    Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

    Published 2025
    “…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”
  12. 6572

    RT-qPCR data tables. by Yoichi Kurokawa (22290520)

    Published 2025
    “…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”
  13. 6573

    Inc exhibits key properties of a Cul3 adaptor in neurons in vivo. by Qiuling Li (390393)

    Published 2025
    “…Neuronal <i>Cul3</i> RNAi decreases <i>Cul3</i> transcript levels but does not significantly alter those of <i>inc</i>. …”
  14. 6574

    Citation patterns of Cochrane Reviews and other systematic reviews: a bibliometric analysis by Louise Olsbro Rosengaard (20439098)

    Published 2025
    “…The time window in which systematic reviews received citations has been progressively decreasing, possibly indicating a trend toward quicker recognition and uptake of these reviews within the academic community. …”
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  19. 6579
  20. 6580

    Distribution of study areas. by Jie Zhang (64655)

    Published 2024
    “…(main findings) The results show the following: (1) the primary term of government innovation preferences has a positive effect on the ecological resilience of resource-based cities, and the secondary term has a negative effect, with a decreasing marginal effect. …”