Showing 1,421 - 1,440 results of 18,438 for search 'significantly ((((largest decrease) OR (we decrease))) OR (((mean decrease) OR (a decrease))))', query time: 0.55s Refine Results
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    Anthelmintics Derived from the Kinase Inhibitor SGI-1776 for the Treatment of Gastrointestinal Worm Infections by Mostafa A. Elfawal (22430138)

    Published 2025
    “…The unexpected SAR of compound <b>15</b> can be explained by computational modeling. We demonstrate the efficacy of optimized compound <b>50</b> as a new oral anthelmintic, which demonstrated better gut restriction properties and significantly reduced the fecundity of T. muris whipworm adults in infected mice. …”
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    Primers used in ChIP-PCR. by Lorenza Cutrone (21144285)

    Published 2025
    “…In lymphatic endothelial cells infected with KSHV and in gastric cancer cells positive for EBV, ectopic HSF2 enhances the expression of lytic genes; While knocking down HSF2 significantly decreases their expression. HSF2 overexpression is accompanied by decreased levels of repressive histone marks at the promoters of the lytic regulators KSHV ORF50 and EBV BZLF1, both characterized by poised chromatin features. …”
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    Primers used in RTqPCR. by Lorenza Cutrone (21144285)

    Published 2025
    “…In lymphatic endothelial cells infected with KSHV and in gastric cancer cells positive for EBV, ectopic HSF2 enhances the expression of lytic genes; While knocking down HSF2 significantly decreases their expression. HSF2 overexpression is accompanied by decreased levels of repressive histone marks at the promoters of the lytic regulators KSHV ORF50 and EBV BZLF1, both characterized by poised chromatin features. …”
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    Prohibitin2 knockdown decreases glioma malignant phenotypes and radio-resistance by inhibiting mitophagy by Xuefei Xue (16496943)

    Published 2025
    “…PHB2 was identified as a cancer-promoting factor in most cancers. However, the function of PHB2 in glioma cells remains unclear. …”
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    Data Sheet 1_Decreased neuronal excitability in hypertriglyceridemia hamsters with acute seizures.docx by Qiuyue Shen (20373266)

    Published 2024
    “…</p>Conclusion<p>Hypertriglyceridemic Apoc2<sup>−/−</sup> hamsters exhibited reduced seizure frequency and decreased cortical neuron excitability. The upregulation of ZDHHC14, leading to increased I<sub>A</sub>, may be a crucial mechanism underlying the observed seizure protection.…”
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    Significant cholesterol genes arranged by day. by Katherine M. Peterson (19746455)

    Published 2024
    “…<p>A. Volcano plots of genes identified as Cholesterol Metabolism Genes. …”
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