DataSheet4_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

DataSheet7_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

DataSheet1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.csv by Mengshi Zhao (20157978)

“…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”

Image 1_Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.jpeg by Bhaswati Roy (2802559)

“…</p>Results<p>At baseline, obese patients had significant brain tissue changes seen in MRI and decreased cognitive scores compared to controls (MoCA 26 vs 28, P = 0.017). …”

Data Sheet 1_Morphophysiological and transcriptomic analyses during the development of microspores and megaspores in Orobanche coerulescens.docx by Kelin Cui (20936231)

“…We also investigated the key regulatory genes in the metabolic pathways of phytohormones that are closely related to the development of microspores and megaspores using transcriptome sequencing technology.…”

Data Sheet 1_ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation.pdf by Marco Túlio R. Gomes (5363324)

“…Using macrophages derived from ZBP1 knockout (KO) mice we demonstrated that ZBP1 partially contributes to IFN-β expression upon B. abortus infection or Brucella DNA transfection. …”

DataSheet9_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.docx by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf by Phillip Pham (407350)

“…However, the roles of freshwater fungal communities remain underexplored compared to bacterial communities in this context.</p>Methods<p>We assessed the impact of anthropological and environmental factors on freshwater mycobiota in an agriculturally dominated water basin in eastern Ontario, Canada. …”

DataSheet6_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

DataSheet1_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

Data Sheet 1_Genome-wide development of SSR molecular markers for modern sugarcane cultivars.docx by Yi Xu (131145)

“…We identified SSR loci in the whole genome of XTT22, a modern sugarcane cultivar. …”

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction by Zhihui Liu (95891)

“…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. …”

DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

<b>Relationship between </b><b>plant</b><b> </b><b>anatomical </b><b>traits and yield among </b><b>different</b><b> winter wheat genotypes in</b><b> </b><b>dry environment</b><b>s<... by Du (17111761)

“…We selected different dryland wheat genotypes(Triticum aestivumL.) and performed a field study to measure their yields. …”

DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

Presentation1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.pdf by Mengshi Zhao (20157978)

“…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”

Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx by Lin Zhang (8926)

“…</p>Results<p>PM2.5 exposure induced distinct alterations in immune cell composition and cell cycle distributions. Notably, we observed significant changes in immune cell populations, including reductions in macrophages (510 to 58 cells), NK cells (445 to 91 cells), and granulocytes (1597 to 1 cells). …”

DataSheet2_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…”

Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... by Lei Qian (292302)

“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”