Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

"…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

"…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"

Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α₁‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

"…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC₅₀: 4.57 vs 7.22 μM), but its selectivity over α₁-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α_1A-, α_1B-, and α_1D-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"

Evolutionary relationships between tooth size and jaw protrusion. حسب Nick Peoples (21593888)

Effects of injury on exploratory behavior. حسب Ella R. Dockendorf (21533334)

Impact of p53 T253I on expression of DNA damage responsive proteins. حسب Nathaniel C. Holcomb (22793595)

Mutant p53 proteins have impaired DNA binding and transcriptional regulation. حسب Nathaniel C. Holcomb (22793595)

Impact of p53 T253I on DNA damage responsive mRNA expression. حسب Nathaniel C. Holcomb (22793595)

Stable incorporation of p53 lentiplasmids is detectible and does not impact cellular growth rates. حسب Nathaniel C. Holcomb (22793595)

Livestock–Crop–Mushroom (LCM) Circular System: An Eco-Friendly Approach for Enhancing Plant Performance and Mitigating Microbiological Risks حسب Dong Liu (115204)

"…Mushroom production using agroforestry biowaste is a great green cycling agriculture alternative. …"

Retention and extinction of operant learning. حسب Ella R. Dockendorf (21533334)

ITPL-1 also reduces female receptivity but does not affect ovipostion in the brown planthopper. حسب Yi-Jie Zhang (713506)

Data Sheet 1_A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia.docx حسب Stephen B. Simons (19931955)

"…Introduction<p>The normal transition to sleep is characterized by a reduction in higher frequency activity and an increase in lower frequency activity in frontal brain regions. …"

Characteristics of the population studied. حسب Diego Rafael Batista (19746556)

"…We conducted 21 in-depth interviews with an intentionally sampled group of participants who had used PrEP at least once in their lifetime, selected through the snowball technique, between April and July 2022. A thematic analysis was conducted with a predominantly inductive approach. …"

Subcellular fractionation of HEK293 p53 wt and mutant proteins. حسب Nathaniel C. Holcomb (22793595)

¹⁷⁷Lu-Labeled Heterodimeric Agent with High Stability Targeting Neovascularization for Tumor Radioligand Therapy حسب Biao Yang (545048)

"…Radiopharmaceutical theranostics holds significant promise in tumor diagnosis and treatment, but suboptimal tumor uptake and retention remain a persistent limitation. …"

Overview of the validated interview guide. حسب Diego Rafael Batista (19746556)

"…We conducted 21 in-depth interviews with an intentionally sampled group of participants who had used PrEP at least once in their lifetime, selected through the snowball technique, between April and July 2022. A thematic analysis was conducted with a predominantly inductive approach. …"

Supplementary file 1_Effects of a personalized PERMA-based intervention on the mental health of junior high school students: a randomized clinical trial.docx حسب Lei Zhang (38117)

"…No significant changes were observed in coping styles, though slight improvements in positive coping tendency (from −0.02 to −0.13) and a slight decrease in negative coping tendency (from −0.02 to −0.01).…"

Table 2_Temporary trigeminal ganglion stimulation can improve zoster-related trigeminal neuralgia: a retrospective study in a single center.docx حسب Kan Yue (1378518)

"…At the six-month follow-up, the mean VAS score decreased from preoperative 6.1 ± 1.5 to 2.5 ± 1.9, demonstrating a statistically significant reduction (t = 4.36, p < 0.05). …"

Table 1_Temporary trigeminal ganglion stimulation can improve zoster-related trigeminal neuralgia: a retrospective study in a single center.docx حسب Kan Yue (1378518)

"…At the six-month follow-up, the mean VAS score decreased from preoperative 6.1 ± 1.5 to 2.5 ± 1.9, demonstrating a statistically significant reduction (t = 4.36, p < 0.05). …"