Image 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... by Mingzheng Duan (11630632)

“…However, continuous cropping of this species has led to various obstacles, such as microbial disease and pest infestation, significantly affecting the production and development of valuable medicinal and food resources. …”

Table 1_Associations between dietary patterns and sarcopenia in aging populations: a community study from eastern China’s Huzhou city.docx by Qi Zhang (28502)

“…Adjusted LR analysis demonstrated that greater adherence to Dietary Patterns 2 [T3 vs. T1: adjusted odds ratio (aOR) = 0.63, 95% confidence interval (CI): 0.40–0.98, p < 0.05] and 3 (T3 vs. …”

All data. by Ke Li (106849)

“…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …”

Table 1_Novel integrated approach modeling proanthocyanidins and bacteriophages to combat multidrug Salmonella Typhimurium in challenged broilers.docx by Hanan S. Al-Khalaifah (12864938)

“…Typhimurium, alongside decreased mortality percentage, which was evidenced by increased expression of MUC-2, β-defensin-1, cathelicidins-2, JAM-2, occludin, and CLDN-1 genes, reduced S. …”

Table_1_Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of Community Engagement Resource Needs and Costs.docx by Nicole A. Stadnick (8788511)

“…Needed resources decreased, albeit with a greater diversity of activities, in later phases of community engagement with Spanish language translation requiring most in the later stage of the study. …”

Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf by Xin Sun (127355)

“…</p>Results<p>The meta-analysis showed a correlation between elevated Eotaxin levels and an increased risk of OSA (OR=1.050, 95% CI: 1.008-1.096; p < 0.05). Furthermore, we found that the increased risk of OSA could be attributed to reduced levels of X-11849 and X-24978 (decreases of 7.1% and 8.4%, respectively). …”

Image_1_Barriers of the CNS transfer rate dynamics in patients with vascular cognitive impairment and dementia.TIFF by Saeid Taheri (339331)

“…</p>Results<p>Longitudinal BBB measurements revealed variable dynamic behavior: after two years, the BBB K_trans increased in 55% of patients and decreased in the remaining 45% unpredictably. We did not find a significant linear model of BBB K_trans versus age for VCID. …”

Readiness Through International Cooperation: Finnish Defence Industrial Strategy in Changing Operational Environment from the Mid-1990s to the Early 2020s by Heikki Roiko-Jokela (22265501)

“…In this paper, we analyse how Finland preserved it in changing operational environment. …”

Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”

Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”

Figure S1-S21 from miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5 by Verena Stiegelbauer (4582930)

“…The miR-196b-5p inhibited DLD1 cells closed the scratch significantly earlier than the inhibitor control cells, whereas the miR-196b-5p overexpression in SW480 resulted in decreased scratch closure (* = significant, p < 0.05; **, p < 0.01; ***, p < 0.001; studentÂ's t-test). …”

Data Sheet 1_Efgartigimod for generalized myasthenia gravis in the extreme elderly (≥80 years): a multicenter retrospective real-world study.pdf by Ye Hong (2580841)

“…At week 4 (1week after the final infusion), the study showed significant reductions in all efficacy measurements: MG-ADL scores decreased by 52.2% ± 30.8% (from 10.9 ± 2.7 to 3.6 ± 2.1), QMG scores by 36.6% ± 28.4% (from 18.2 ± 7.0 to 11.7 ± 8.3), MGC scores by 48.2% ± 33.4% (from 17.8 ± 7.5 to 9.0 ± 8.6). …”

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> by Elena Suleymanova (22195777)

“…We also observed disruption of the IGF system, characterized by decreased IGFBP-5 protein levels in the hippocampus and downregulation of <i>Igfbp5</i> mRNA in both hippocampus and cortex. …”

Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx by Olubukunmi Amos Ilori (22446976)

“…The miR-10a-5p, miR-24-3p, and miR-130a-3p, were not detected in raw buffalo milk. Therefore, we simulated the gastrointestinal digestion using INFOGEST 2.0 and extracted extracellular vesicles from the digest. …”

Data Sheet 2_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

DataSheet1_Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic reti... by Letizia Pelusi (9606879)

“…In the last years, mesenchymal stromal cells (MSCs) and neurotrophins like Nerve Growth Factor (NGF), have garnered significant attention as innovative therapeutic approaches targeting DR-associated neurodegeneration. …”

Table 3_Ranges, temporal trend, and determinants of novel obesity indices in middle-aged and older Chinese population: insights from a nationally representative and longitudinal st... by Liufang Huang (12397954)

“…Over the five-year period, WHtR, CVAI, and LAP increased significantly (β = 0.00489, β = 4.51607, β = 6.37441; all p < 0.001), while ABSI decreased (β = −0.00048, p < 0.001). …”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …”

Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx by Olubukunmi Amos Ilori (22446976)

“…The miR-10a-5p, miR-24-3p, and miR-130a-3p, were not detected in raw buffalo milk. Therefore, we simulated the gastrointestinal digestion using INFOGEST 2.0 and extracted extracellular vesicles from the digest. …”