Overcoming the Limitations of Transition-Metal Catalysis in the Chemoenzymatic Dynamic Kinetic Resolution (DKR) of Atropisomeric Bisnaphthols by Kun Wang (134525)

“…Therefore, we developed an efficient DKR method to access chiral BINOLs from racemic derivatives under dual copper and enzyme catalysis. …”

Primers used for qPCR gene expression analysis. by Yejin Kim (740789)

“…Analysis of GEO datasets (GSE132606, GSE25417, GSE67848) and TCGA HCC data revealed that while SLC2A2 expression decreases with HCC progression, stemness-associated genes, including SOX2 and POU5F1, are upregulated. …”

Connectivity between the left nucleus accumbens and two clusters. by Karel Joineau (21799908)

“…After intervention there was a significant decrease in the FR group (mean at V1: 0.249 ± 0.094, mean at V5: 0.130 ± 0.101, difference: −0.119 ± 0.097, p < 0.001) and a significant increase in the SM group (mean at V1: 0.156 ± 0.113, mean at V5: 0.287 ± 0.107, difference: 0.131 ± 0.066, p < 0.001). …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Summary of KEGG enrichment analysis. by Zeynab Hosseinpoor (19762319)

“…While the expression levels of <i>IRS2</i>, <i>FOXO1</i>, and <i>ERK2</i> (<i>MAPK1</i>) were significantly decreased, the <i>SERPINF1</i> gene exhibited high expression simultaneously. pAAV-delivered <i>MIR-96</i> had no adverse effect on the viability of human RPE cells. …”

<i>SLC2A2</i> is associated with IGF1R pathways differentiation. by Yejin Kim (740789)

Enrollment flow-chart. by Marco Carbonara (11483575)

Primer sequences for RT-qPCR. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

siRNA sequences and negative controls sequences. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

Antibodies used in the study. by Wenlong Shen (9313937)

“…Data from TCGA showed that NCOA4 shows greater downgrade in tumor tissues than in non-tumor tissues and the overall survival (OS) of patients with low NCOA4 expression was significantly shorter than that of patients with high NCOA4 expression.The qPCR results showed that NCOA4 was expressed at low levels in cholangiocarcinoma tissue specimens; the mRNA expression of NCOA4 decreased after knocking down NCOA4 in cells. …”

Histogram of the area factorψ. by Hong Zhang (25820)

“…The measured <i>I</i>_s decreases following a power-law trend as <i>β</i> and <i>D</i> increase, with weathering reducing the sensitivity of <i>I</i>_s to <i>β</i> but not significantly altering its sensitivity to <i>D</i>. …”

Raw dataset Fig. 6. by Hong Zhang (25820)

“…The measured <i>I</i>_s decreases following a power-law trend as <i>β</i> and <i>D</i> increase, with weathering reducing the sensitivity of <i>I</i>_s to <i>β</i> but not significantly altering its sensitivity to <i>D</i>. …”

Effect of sample size on reproducibility. by Jan Willem Koten (17743224)

Effect of corrections on connectivity maps. by Jan Willem Koten (17743224)

Active DNA Demethylation Mediated by <i>OsGADD45a2</i> Regulates Growth, Development, and Blast (Magnaporthe oryzea) Resistance in Rice by Ganghua Zhou (9283406)

“…In <i>OsGADD45a2</i> overexpression lines, significant decreases in CG and CHG methylation levels were observed in protein-coding genes, leading to their upregulation. …”

Reproducibility of response time and brain measures. by Jan Willem Koten (17743224)

Fluorescence Imaging of Neuroblastocyte Differentiation and Parkinson’s Brain Tissue Lesions Examined by a Norepinephrine-Activated Molecular Probe by Huming Yan (9917374)

“…Compared to the previously developed probe <i><b>SXU-NEQ</b></i>, the self-fluorescence intensity of probe <i><b>DQF</b></i> decreased significantly (I<i>_<b>DQF</b></i>/I<i>_{<b>SXU‑NEQ</b>}</i> = 35%). …”